A
microfluidic device is a small tool or apparatus that uses tiny channels or tubes to manipulate and control fluids on a very small scale. It helps scientists and researchers perform experiments and tests involving small amounts of liquid samples.
Full definition
Combining experiments
in microfluidic devices with numerical simulations of a cellular automaton, we have developed a framework for quantifying strain mixture versus segregation in the coverage patterns that emerge from bacterial expansion competition on 2D flat surfaces.
«We thought it would be incredibly useful if we could mimic jellyfish and functionalise
microfluidic devices with long tentacles,» says Karp.
This represents a new way to build
microfluidic devices for processing environmental or medical samples on the very small scale for testing and diagnostics, the work suggests.
In tandem with this trend,
microfluidic devices using conductive liquid metals have been increasingly employed as wearable pressure and strain sensors.
«Mammalian fertilization, caught on tape: Using a
new microfluidic device called the «IVF chip,» scientists obtain the first images with both high spatial and temporal resolution of the initial steps of fertilization.»
With the three - year grant, Vanapalli and his collaborators Boyd Butler in the Department of Biological Sciences and Everardo Cobos at the Texas Tech University Health Sciences Center, will
build microfluidic devices that mimic blood flow to study how tumor cells move inside capillaries, how they squeeze through tight spaces, whether they are subject to fragmentation and how they become stuck.
The findings, the result of microscopic analysis of bacteria
inside microfluidic devices, were made by MIT postdoc Roberto Rusconi, former MIT postdoc Jeffrey Guasto (now an assistant professor of mechanical engineering at Tufts University), and Roman Stocker, an associate professor of civil and environmental engineering at MIT.
The company
makes microfluidic device (chip), which allows intracellular delivery of genetic material via mechanical squeezing of cells.
Nordin said the advantages of 3D printing for
microfluidic device fabrication are already well - known and that their method, digital light processing stereolithography (DLP - SLA), is an especially promising lower - cost approach.
Wei Wang and Zhi Ping Wang at the A * STAR Singapore Institute of Manufacturing Technology, De Yun Wang at the National University of Singapore and co-workers have now developed the
first microfluidic device that enables the direct observation of cilia and their beating frequency on a polyester membrane [1].
«Skin - mounted
microfluidic devices from the Rogers group allow us, for the first time, to determine sweat and electrolyte loss continuously, as it occurs in the pool during swimming, without any adverse impact on our athletes.
In addition to new understanding of the forces governing microswimmers and their environments, the vortex technique could help prevent biofilms from forming and
disrupting microfluidic devices, the authors suggested.
The discovery helps scientists understand the interaction of microswimmers and could help prevent films from forming in
microfluidic devices such as labs - on - a-chip.
The current design is a prototype that could be integrated with
other microfluidic devices to analyze whole blood samples in parallel to diagnose anemia and other underlying factors that could contribute to the disease.
Wardle says the combination of carbon nanotubes and multilayer coatings may help finely
tune microfluidic devices to capture extremely small and rare particles, such as certain viruses and proteins.
Developed by Assistant Professor Gretchen Mahler and Binghamton biomedical engineering alumna Courtney Sakolish PhD» 16, the reusable, multi-layered and
microfluidic device incorporates a porous growth substrate, with a physiological fluid flow, and the passive filtration of the capillaries around the end of a kidney, called the glomerulus, where waste is filtered from blood.
The title of the Science Translational Medicine paper is «A Soft,
Wearable Microfluidic Device for the Capture, Storage, and Colorimetric Sensing of Sweat.»
A Northwestern University research team has developed a first - of - its - kind soft,
flexible microfluidic device that easily adheres to the skin and measures the wearer's sweat to show how his or her body is responding to exercise.
In addition, these so - called
microfluidic devices differ from other separators because they contain no moving parts, which could increase reliability.
The results were published in the journal Lab on a Chip (Lab on a Chip 17 (19), 3291 - 3299) in an article called: «Magnetic particles assisted capture and release of rare circulating tumor cells using wavy - herringbone
structured microfluidic devices.»
«WPI brings an outstanding theoretical tool that allows us to understand how microscale objects, such as sperm, interact with their environment; and we are able to design this know - how into
real microfluidic devices, clinically validate what we designed, and experimentally improve it into a real - world application.»
Liu's
microfluidic device achieves two key standards by which the success of CTC devices is measured: high capture efficiency and high selectivity.
Using QUASR, either in a
portable microfluidic device or simple field laboratory, a user can get a definitive yes or no result in about half an hour.
«Enhancing lab - on - a-chip peristalsis with electro - osmosis: Researchers have conducted analyses to electrically increase liquid flow in pump -
free microfluidic devices.»
Other more
recent microfluidic devices are also hampered by the noise of measuring cell migration on flat surfaces, when the direction of migration changes frequently interfering with the velocity measurements.»
Brown University engineers have demonstrated a technique for making 3 - D - printed biomaterials that can degrade on demand, which can be useful in making intricately
patterned microfluidic devices or in making cell cultures than can change dynamically during experiments.
The technique could be useful could be useful in
fabricating microfluidic devices, creating biomaterials that respond dynamically to stimuli and in patterning artificial tissue.
Researchers at BYU are the first to 3D - print a
viable microfluidic device small enough to be effective at a scale much less than 100 micrometers.
In a study of 51 patients, researchers used a state - of - the
art microfluidic device to capture circulating pancreas epithelial cells in 33 percent of patients with early pancreatic lesions and no clinical diagnosis of cancer.
We designed a
customized microfluidic device for the encapsulation of Dental Pulp Stem Cells (DPSCs) and Neural Stem Cells (NSCs) for further transplantation into an ex vivo murine Spinal Cord Injury (SCI) model.
Dec. 6, 2016 — A new
microfluidic device containing human cells that faithfully mimics the behavior of the blood - brain barrier is providing new insights into brain inflammation, the silent killer.
And while there are already sorting methods that select the fastest - swimming sperm, a new
microfluidic device also ensures that they're the healthiest.
Swiss researchers have revealed a new, battery -
powered microfluidic device capable of detecting different biomarkers in very small quantities of blood.
«Our technology will provide significantly higher forces and faster impact cycles than have previously been possible, and by building these tools
onto microfluidic devices, we can leverage a host of other on - chip diagnostics and imaging tools and can collect the cells after testing for longer - term studies,» said Valentine.
Prof. Shen and her unit say that, in the future, nanoplasmonic materials may even be integrated with emerging technologies, such as wireless systems
in microfluidic devices, allowing users to take readings remotely and thereby minimizing the risk of contamination.
Prior studies
of microfluidic devices have shown that motility of the sperm sample increased to almost 100 percent and morphology of the isolated sperm also was improved after microfluidic sorting.
Brilliant minds reach back to childhood to help them develop tiny transistors, study particle separation,
make microfluidics devices, and fight cancer
«As a simpler, more scalable, and spatially selective method, this texturing of graphene and graphite exploits the thermally induced transformation of shape - memory thermoplastics, which has been previously applied to
microfluidic device fabrication, metallic film patterning, nanowire assembly, and robotic self - assembly applications,» added Nam, whose group has filed a patent for their novel strategy.