Sentences with phrase «microfluidic devices for»
Open access microfluidic device for the study of cell migration during chemotaxis.
https://www.intelligent-imaging.com/ Not exact matches
The discovery could lead to new microfluidic devices and better methods for separating salt water from crude oil.
Although some of my research focuses on the development of nanoelectronic devices for life science applications (as well as for telecommunications and radio astronomy), most of my research efforts are based on the use of microfluidic chips (MFCs) with molecular biology.
As it can take weeks to grow human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended times.
The idea could be useful for shunting drops around microfluidic devices, giving greater control over chemical reactions.
Chemist John Pojman of Louisiana State University in Baton Rouge adds that such roving droplets «might be useful as a pumping mechanism for microfluidics, converting chemical energy to mechanical motion in small devices,» such as the microfluidic labs - on - a-chip many researchers are developing as diagnostic machines.
The device continuously monitors conditions within the microfluidic chip, including oxygen levels, temperature, and pH, to ensure the optimum environment for cell growth.
Launched from Rogers» group through Northwestern's Innovation and New Ventures Office (INVO), startup Epicore Biosystems has established large volume manufacturing capabilities for these microfluidic devices.
«Skin - mounted microfluidic devices from the Rogers group allow us, for the first time, to determine sweat and electrolyte loss continuously, as it occurs in the pool during swimming, without any adverse impact on our athletes.
«Soft, microfluidic «lab on the skin» developed for sweat analysis: Low - cost wearable electronic device collects and analyzes sweat for health monitoring.»
With the technology on track for commercialization, Rogers» team, including Dr. Roozbeh Ghaffari, the director of translational science at CBIE, is continuing to test the microfluidic devices in scaled studies with an expanding collection of partners.
Attendees at the astrobiology meeting in Arizona showcased an assortment of high - tech devices for next - generation exploration, ranging from microfluidic «life analyzers» and integrated nucleic acid extractors for studying «Martian metagenomics» to exquisitely sensitive, miniaturized organic chemistry labs for spotting tantalizing carbon compounds and minerals at microscopic scales.
Erkan Tüzel, left, associate professor of physics, biomedical engineering, and computer science at Worcester Polytechnic Institute (WPI), and PhD candidate James Kingsley examine a microfluidic sperm sorting device called SPARTAN (Simple Periodic ARray for Trapping And IsolatioN).
«Thus, thanks to this unique program, we teamed up with McGill's bioengineers and microfluidic and mathematical modelling experts to create the device required for our study.»
And compared to other techniques used for assisted reproductive technologies, the use of the microfluidic device resulted in significantly lower rates of DNA damage and improved sperm recovery using this method.
Inside the microfluidic device, each cell is assigned one channel - track along which the cell will migrate for several hours.
In an effort to overcome these limitations, a team at the Wyss Institute for Biologically Inspired Engineering led by its Founding Director, Donald Ingber, M.D., Ph.D., had previously engineered a microfluidic «Organ - on - a-Chip» (Organ Chip) culture device in which cells from a human intestinal cell line originally isolated from a tumor were cultured in one of two parallel running channels, separated by a porous matrix - coated membrane from human blood vessel - derived endothelial cells in the adjacent channel.
An automated microscope takes images every 20 minutes at multiple locations in the microfluidic device, and multiple devices at once, allowing for the tracking of dozens of cells in one experiment.
Artificial muscles are well suited to powering microfluidic pumps, for example, on the lab - on - a-chip devices prized by medicine and industry.
Brown University engineers have demonstrated a technique for making 3 - D - printed biomaterials that can degrade on demand, which can be useful in making intricately patterned microfluidic devices or in making cell cultures than can change dynamically during experiments.
The researchers showed that they could use alginate as a template for making lab - on - a-chip devices with complex microfluidic channels.
«This means that the system will open up new options for biosensing particles within microfluidic devices.»
The work for the making of the microfluidic devices at the BioMEMS Resource Center was supported by the National Institute of Biomedical Imaging and Bioengineering of the NIH (5P41EB002503 - 12).
The results, published in Nanoscale, have profound implications for healthcare diagnostics and open up opportunities for producing pre-packaged microfluidic platform blood or urine testing devices.
«Gently rotating small organisms, cells for the first time in a microfluidic device.»
Microfluidic perifusion and imaging device for multi-parametric islet function assessment.
In the third project, Shusteff, a microsystems engineer in the Center for Micro and Nanotechnology, is developing a microfluidic device to separate malarial parasites by their viability.
The labelling is for acetylated tubulin in red (identifying all axons), and green for the cell permeable dye calcein, which is only applied on the axonal side of the chambers (top half) and allows the identification of those neuronal cell bodies (bottom half) that have extended axons to the other side of the microfluidic device.
«Our technology will provide significantly higher forces and faster impact cycles than have previously been possible, and by building these tools onto microfluidic devices, we can leverage a host of other on - chip diagnostics and imaging tools and can collect the cells after testing for longer - term studies,» said Valentine.
Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed hydrogel based microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign