«Skin - mounted
microfluidic devices from the Rogers group allow us, for the first time, to determine sweat and electrolyte loss continuously, as it occurs in the pool during swimming, without any adverse impact on our athletes.
Not exact matches
The discovery could lead to new
microfluidic devices and better methods for separating salt water
from crude oil.
In addition to new understanding of the forces governing microswimmers and their environments, the vortex technique could help prevent biofilms
from forming and disrupting
microfluidic devices, the authors suggested.
The discovery helps scientists understand the interaction of microswimmers and could help prevent films
from forming in
microfluidic devices such as labs - on - a-chip.
The scientists, who come
from Princeton and the Georgia Institute of Technology, developed a new
microfluidic device that traps and vertically positions tiny objects faster than before.
Launched
from Rogers» group through Northwestern's Innovation and New Ventures Office (INVO), startup Epicore Biosystems has established large volume manufacturing capabilities for these
microfluidic devices.
Developed by Assistant Professor Gretchen Mahler and Binghamton biomedical engineering alumna Courtney Sakolish PhD» 16, the reusable, multi-layered and
microfluidic device incorporates a porous growth substrate, with a physiological fluid flow, and the passive filtration of the capillaries around the end of a kidney, called the glomerulus, where waste is filtered
from blood.
New adhesive materials and
microfluidic designs maintain water - tight seals to the skin to capture and analyze sweat while preventing surrounding water
from entering the
device's microscopic channels.
The
device is a unique example of
microfluidics technology, sometimes called a lab - on - a-chip, that pushes water around in microscopic tubes and reservoirs made
from the same cellophanelike plastic as soft contact lenses.
Attendees at the astrobiology meeting in Arizona showcased an assortment of high - tech
devices for next - generation exploration, ranging
from microfluidic «life analyzers» and integrated nucleic acid extractors for studying «Martian metagenomics» to exquisitely sensitive, miniaturized organic chemistry labs for spotting tantalizing carbon compounds and minerals at microscopic scales.
The team
from the Massachusetts General Hospital plans to use the
microfluidic devices in synergy with some more sophisticated molecular biology tools and identify the control factors of cell migration speed.
In an effort to overcome these limitations, a team at the Wyss Institute for Biologically Inspired Engineering led by its Founding Director, Donald Ingber, M.D., Ph.D., had previously engineered a
microfluidic «Organ - on - a-Chip» (Organ Chip) culture
device in which cells
from a human intestinal cell line originally isolated
from a tumor were cultured in one of two parallel running channels, separated by a porous matrix - coated membrane
from human blood vessel - derived endothelial cells in the adjacent channel.
In order to develop a system that more closely replicates the metabolic differences among hepatocytes, the research team developed a
microfluidic device that distributes hormones or other chemical agents across a 20 - to 40 - cell - wide sample of hepatocytes in such a way that the effects on the liver cells vary
from one side to the other.
A theoretical and experimental study of the electrophoretic extraction of ions
from a pressure driven flow in a
microfluidic device.
In theory, scientists could remove immune cells
from a patient, run them through the
microfluidic device and expose them to a viral protein, and then put them back in the patient.
In 2013, his team developed an organ - on - a-chip
microfluidic culture
device that modeled the human kidney's proximal tubule, which is anatomically connected to the glomerulus and salvages ions
from urinary fluid.
Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery
devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed hydrogel based
microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated
from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign