More recently, Professor Bargmann has taken chemotaxis studies to new levels with the development of an easy to replicate
microfluidic system with which to quantify movement in both time and space in response to attractive odors.
The team is also testing the resolution of
the microfluidic system with other reagents and materials, bringing researchers one step closer to viewing live biological mechanisms in action at the highest levels of resolution possible.
Not exact matches
Prof. Shen and her unit say that, in the future, nanoplasmonic materials may even be integrated
with emerging technologies, such as wireless
systems in
microfluidic devices, allowing users to take readings remotely and thereby minimizing the risk of contamination.
Fussenegger's group developed the genetic network; Professor of Biosystems Engineering Andreas Hierlemann and his team tested the acidity sensor
with the aid of
microfluidic platforms; and Jörg Stelling, a professor of computational
systems biology, modelled it in order to estimate the dynamics of the insulin production.
Northwestern University professor John A. Rogers is collaborating
with a broad collection of partners including Gatorade, the Seattle Mariners, the U.S. Air Force and Shirley Ryan AbilityLab to bring his wearable
microfluidic sweat analytics
system into widespread distribution.
«The intimate skin interface created by this wearable, skin - like
microfluidic system enables new measurement capabilities not possible
with the kinds of absorbent pads and sponges currently used in sweat collection,» said John A. Rogers, who led the multi-institution research team that created the «lab on the skin.»
Such micro-structured surfaces have helped design new surfaces that mimic surfaces found in nature, such as self - cleaning surfaces, reduced - drag surfaces, surfaces capable of transporting liquids in
microfluidic systems, variants
with anti-icing or heat transfer properties, and even surfaces that facilitate oil - water separation.
The microfabricated chip could be mass produced and integrated easily
with existing
microfluidic systems.
I noticed this problem three years ago, when I was at a synthetic biology company where I built some of these
microfluidic systems and mechanical machines that interact
with them.
To better study circulating tumor cells, the researchers collaborated
with physician - scientists and industry engineers to develop a
microfluidics system that separates these large cells into a concentrated sample.
Large - scale and effective studies of biological molecules
with a different structural basis such as proteins, nucleic acids, carbohydrates, lipids and numerous metabolites (including e.g. fatty acids, amino acids, purines, pyrimidines or steroids) is currently highly attractive because of the availability of modern instruments and tools for both separation and analysis (2 - D chromatographs, capillary electrophoresis
systems,
microfluidics, mass spectrometers, powerful NMR spectrometers, DNA / RNA arrays and others).
And most researchers working on this kind of chip were working
with closed
microfluidic systems, which allow fluid to flow in and out but do not offer an easy way to manipulate what is happening inside the chip.
As outlined below, we used a
microfluidic quantitative PCR (qPCR)
system to elucidate the gene expression profiles of individual human oocytes and small numbers of cumulus cells using a combination of a large number of samples and targets [12], and then extended our studies via the use of parthenogenesis, in conjunction
with gene expression profiling, as a functional assay of cytoplasmic maturation of oocytes.
The postdoc will work under the joint supervision of Prof. Weitz and Dr. Raoul Rosenthal to pursue research projects on directed evolution of antibodies
with microfluidic systems.
Comprised of a
microfluidic plate and controller, the
system delivers programmable, hands - free control and, importantly, is fully compatible
with microscope stages for dynamic live cell imaging.