Microfluidic systems refer to tiny devices or systems that manipulate very small amounts of fluids, usually in the range of microliters or nanoliters. They use channels, valves, and pumps at a microscopic scale to control the movement and mixing of these fluids. These systems have various applications like medical diagnostics, lab-on-a-chip devices, chemical analysis, and drug delivery.
Full definition
More recently, Professor Bargmann has taken chemotaxis studies to new levels with the development of an easy to replicate
microfluidic system with which to quantify movement in both time and space in response to attractive odors.
Because the field of microfluidics is a relatively immature field, numerical simulations
of microfluidic systems can be extremely valuable both in terms of providing a research tool and as an efficient design and optimization tool.
Such micro-structured surfaces have helped design new surfaces that mimic surfaces found in nature, such as self - cleaning surfaces, reduced - drag surfaces, surfaces capable of transporting liquids
in microfluidic systems, variants with anti-icing or heat transfer properties, and even surfaces that facilitate oil - water separation.
For studies at the molecular level, Ismagilov will
develop microfluidic systems capable of rapidly generating, manipulating and assaying protein aggregates of various sizes, shapes and compositions.
Furthermore, most researchers working on this kind of chip were working with
closed microfluidic systems, which allow fluid to flow in and out but do not offer an easy way to manipulate what is happening inside the chip.
«The intimate skin interface created by this wearable, skin -
like microfluidic system enables new measurement capabilities not possible with the kinds of absorbent pads and sponges currently used in sweat collection,» said John A. Rogers, who led the multi-institution research team that created the «lab on the skin.»
Despite its common use in
passive microfluidic systems, there's been limited development of active magnetic actuation methods, mainly due to the limitations of conventional electromagnetic sources.
The Stanford team is currently developing new applications for EPM actuation in
ferro microfluidic systems, as well as optimizing the EPM design.
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Traditional microfluidic systems use tubes, valves, and pumps,» says Udayan Umapathi, a researcher at the MIT Media Lab, who led the development of the new system.
ScanDrop is an all - in - one
microfluidic system for detecting and reporting the presence of bacteria in drinking water (Golberg, et al., 2014).
On the bioengineering side, Westervelt's group has developed hybrid Integrated Circuit / Microfluidic chips -
programmable microfluidic systems that can trap, move, sort, and assemble biological cells and small particles in fluids.
Many scientists are working to
develop microfluidic systems — known as labs - on - a-chip — that can mix small amounts of chemical reagents or biological molecules.
And most researchers working on this kind of chip were working with
closed microfluidic systems, which allow fluid to flow in and out but do not offer an easy way to manipulate what is happening inside the chip.
«Given their small, strong and switchable properties, EPMs can be used for active magnetic actuation
in microfluidic systems, a method with many potential applications, but currently limited by existing electromagnetic sources,» says José I. Padovani, the lead author on this paper.
Inconsistencies in a previous conceptual explanation of the stinging cell mechanism were identified using
a microfluidic system and mathematical models.
In addition, the researchers integrated the sensor into
a microfluidic system made of micrometer - sized channels containing nanoliters of liquids.
I noticed this problem three years ago, when I was at a synthetic biology company where I built some of
these microfluidic systems and mechanical machines that interact with them.
To better study circulating tumor cells, the researchers collaborated with physician - scientists and industry engineers to develop
a microfluidics system that separates these large cells into a concentrated sample.
A recent paper in the Proceedings of the National Academy of Sciences (PNAS) describes how researchers at KTH / SciLifeLab were able to find more productive yeast and the underlying genetic alterations using picoliter droplet screening in
a microfluidic system.