The project will rely on
microfluidics techniques pioneered by Beebe.
Not exact matches
In addition to new understanding of the forces governing microswimmers and their environments, the vortex
technique could help prevent biofilms from forming and disrupting
microfluidic devices, the authors suggested.
The
technique relies heavily on custom - built
microfluidic chips.
Abate's researchers are now working to improve those statistics, and his company, Mission Bio, in South San Francisco, California, is developing commercial versions of the
microfluidic chips to give other scientists access to the
technique.
In a paper published in Nature Methods, postdoctoral fellows Naomi Habib, Inbal Avraham - Davidi, and Anindita Basu; core institute members Feng Zhang and Aviv Regev; and their colleagues reveal DroNc - Seq, a single - cell expression profiling
technique that merges sNuc - Seq with
microfluidics, allowing massively parallel measurement of gene expression in structurally - complicated tissues.
Instead of just making molds, Khine ultimately developed a
technique to make
microfluidics chips directly from Shrinky Dink plastic.
The researchers also used the new
technique, called
microfluidic dissection, in which large numbers of yeast are grown in a chamber bathed with liquid food containing a constant concentration of nutrients.
Using a new
technique they call «in - air
microfluidics», University of Twente scientists succeed in printing 3D structures with living cells.
During this webinar, our expert panelists will describe these methods and present breakthrough research data obtained using novel experimental approaches, including immunoassays,
microfluidics - based
techniques, and high - content screening immunophenotypic assays.
Molecular biology and
microfluidics have spawned powerful
techniques for isolating and manipulating small amounts of biological materials, making salivary diagnostics possible.
And compared to other
techniques used for assisted reproductive technologies, the use of the
microfluidic device resulted in significantly lower rates of DNA damage and improved sperm recovery using this method.
Sperm sorting methodologies based on
microfluidic procedures are a valuable option since these
techniques eliminate the damaging centrifugation steps.»
The team, led by scientists from Harvard University and Lawrence Livermore National Laboratory, employed a
microfluidic assembly
technique to produce microcapsules that contain liquid sorbents, or absorbing materials, encased in highly permeable polymer shells.
Brown University engineers have demonstrated a
technique for making 3 - D - printed biomaterials that can degrade on demand, which can be useful in making intricately patterned
microfluidic devices or in making cell cultures than can change dynamically during experiments.
The
technique could be useful could be useful in fabricating
microfluidic devices, creating biomaterials that respond dynamically to stimuli and in patterning artificial tissue.
Based on this change, you can use this
technique to measure the mass of the biomolecule, and confirm whether it survives exposure to ionized gas during encapsulation within the
microfluidic platform.
Unlike atomic force microscopy,
microfluidics is a high - throughput screening
technique, but additional work is required to assess the efficiency of this type of biophysical - based sorting for stem cell enrichment.
«A
microfluidic device that sorts cells based on their mechanical properties could offer cost and labor advantages over current methods and may provide sufficient enrichment to serve as an alternative or additional approach to antibody - based
techniques,» Sulchek says.
The
microfluidic device designed by his team captures cells based on their distinct internal structure — a mechanical analysis instead of the blood chemistry analysis used in conventional medical diagnostic
techniques.
DEP can be thought of as a low - frequency analogue of optical tweezers, and it has become a popular
technique in the
microfluidics and lab - on - a-chip fields because it is so simple.
We work across disciplines and use a variety of
techniques including
microfluidics, standard microscopies (electron, optical, fluorescence, confocal), spectroscopies (fluorescence, UV, CD), scattering
techniques (X-ray, light), protein expression and characterization and cell - free gene expression to investigate the utility of coacervate microdroplets as robust reaction compartments and cellular mimics.
«By getting stuff into the cells, you can understand the disease and hence design therapies,» says Armon Sharei, lead author of a recent article on a new and vector - free
microfluidic transfection
technique, addressing the transfection challenge.
The approaches combine theoretical studies — including statistical physics of non-equilibrium systems — and a variety of experimental
techniques such as optical and electron microscopy, as well as
microfluidics and micropatterning, optogenetics, or mechanical micromanipulation using optical or magnetic tweezers.
Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab
techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation
techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed hydrogel based
microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization
techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign