Sentences with phrase «microglial responses»

Not exact matches

Also worth noting is that ADEM causes an inflammatory response in the brain, primarily in the microglial cells.

Shankaran, M.; Marino, M. E.; Busch, R.; Keim, C.; King, C.; Lee, J.; Killion, S.; Awada, M.; Hellerstein, M. K. Measurement of brain microglial proliferation rates in vivo in response to neuroinflammatory stimuli: application to drug discovery.

Moreover, recent data also show that in response to brain damage caused by aging, amyloid deposition, demyelination, and other insults, microglial cells activate several genes, including APOE, in order to more efficiently scavenge and clear tissue debris that are very rich in cholesterol due to the natural composition of the brain, which is mostly made of fats.

Microglial depletion alters the brain neuroimmune response to acute binge ethanol withdrawal

While it is known that microglia immune activity changes with aging, which response is affected first — the pro-inflammatory or the anti-inflammatory — or, more importantly, when microglial aging begins is not clear, says Jyoti Watters of the University of Wisconsin - Madison and lead investigator of the study.

''... microglial proliferation can be induced under inflammatory responses in the brain with an increased production of ROS; therefore, microglia accumulate 8 - oxoG in nuclear DNA.»