The researchers found that the 135 -
microgram vaccine triggered antibodies and produced only mild side effects.
Not exact matches
Tests in macaque monkeys also showed that a single
vaccine dose of only 50
micrograms provided strong protection against exposure to Zika virus five weeks later.
The method is much less cumbersome than dealing with chicken eggs, and because the
vaccine is so easy to produce, the company intends to use 135
micrograms of hemagglutinin in each dose of
vaccine — 3 times higher than current flu
vaccines — in hopes of getting better protection.
Total
vaccine supply will depend on several other unknowns, including whether 15
micrograms of antigen is enough — as is the case with seasonal
vaccine — and whether one or two shots are needed.
Initially, all of the makers of inactivated
vaccine had trouble with the «potency assay» used to ensure that 15
micrograms of influenza antigens are present in each dose.
The few remaining mercury - containing
vaccines contain < 1
microgram.
Like the multidose influenza
vaccines, some multidose meningococcal meningitis
vaccines and tetanus toxoid (booster)
vaccines (not recommended for children under six years of age) also contain thimerosal as a preservative, in amounts ranging from 12.5 to 25
micrograms per dose.27, 28 As of 2016, some other childhood
vaccine preparations, such as the multidose DTaP and the DTaP / Hib combination
vaccines, still utilize thimerosal in the manufacturing process.