To determine whether the aforementioned segments of chromosomes 23 and 25 were inherited IBD, we genotyped polymorphic
microsatellite markers in each region.
Funded by the National Zoological Gardens of South Africa, Rufford's Small Grants for Nature, and the National Geographic Society, Parusnath is developing and
testing microsatellite markers similar to those used in human parentage tests to establish the genetic relatedness of Sungazers in different populations across the species» distribution.
With these tools in hand, researchers at Genethon - CEPH, aided by Genethon's expertise in automation, mapped 816
microsatellite markers onto human chromosomes, producing what they call a «second - generation» genetic map.
Here, we used parentage analysis with
multilocus microsatellite markers to measure how varying levels of genetic introgression with non-native rainbow trout (Oncorhynchus mykiss) affect reproductive success (number of offspring per adult) of native westslope cutthroat trout (Oncorhynchus clarkii lewisi) in the wild.
So the Kyoto researchers developed a set
of microsatellite markers, short bits of repeated sequences of DNA that tend to evolve very quickly.
For the new study, which is published today in the Proceedings of the Royal Society B, Bowman and his colleagues collected samples from 38 L. mariae palms in Palm Valley and 100 L. rigida palms in the Roper, Nicholson, and Gregory rivers and compared
the microsatellite markers.
The French researchers plan to add another 4000
microsatellite markers to the map this year, increasing its resolution fivefold.
With the recent publication of a large data set of 763
microsatellite markers — short stretches of DNA that are repeated in the genome — from 53 populations in the Human Genome Diversity Project, evolutionary geneticists William Amos and Joe Hoffman of the University of Cambridge in the United Kingdom had enough genomic data to test both models.
This allele maps to an interval between
the microsatellite markers D14Mit14 and D14Mit80 located at 10.0 cM and 13.5 cM.
Using deCODE's national genealogy database, 100 of these patients were found to fall into 39 families, and a genome - wide scan was conducted with 1000
microsatellite markers.
deCODE successfully mapped the asthma gene through a genome - wide linkage analysis using approximately 1000
microsatellite markers and involving 175 families across Iceland.
Nearly 500 volunteer patients and more than 300 unaffected relatives were genotyped with 900
microsatellite markers.
For the remaining 14 samples, a match was nearly perfect, with only one or two of
the microsatellite markers varying, typically by only one repeat unit, as might be expected through microsatellite instability within a pedigree.
Microsatellite markers used for screening tests are on the same chromosome as the disease gene.
Microsatellite markers can become separated from the target gene during recombination.