Sentences with phrase «microsatellite repeats»

A synthetic molecule can surmount barriers to transcription elongation at repressive microsatellite repeats that cause Friedreich's ataxia.

The mutation identified is a microsatellite repeat within intron 7 of the gene.

Not exact matches

So the Kyoto researchers developed a set of microsatellite markers, short bits of repeated sequences of DNA that tend to evolve very quickly.

Extra bases are easily added or lost when the DNA is copied, so the number of repeats in each of these stretches, known as microsatellites, varies widely from one individual to another.

But the chance that a given microsatellite will change from, say, 11 CA (cytosine and adenine) repeats to 12 is on the order of one in a few hundred.

The distance between these neighboring sequences, called primers, differs between each individual coral due to the number of times the microsatellites are repeated, providing valuable information on the relatedness of different individuals.

Microsatellites are a gene mapper's dream: not only are they repeated different numbers of times in different people, but they are scattered throughout the genome.

After extracting tiny amounts of ancient DNA from the mummies» bones, the researchers amplified 16 short tandem repeats (short sequences in the DNA that create a genetic fingerprint) and eight polymorphic microsatellites (hereditary molecular markers) to testable quantities using techniques commonly employed in criminal or paternity investigations.

With the recent publication of a large data set of 763 microsatellite markers — short stretches of DNA that are repeated in the genome — from 53 populations in the Human Genome Diversity Project, evolutionary geneticists William Amos and Joe Hoffman of the University of Cambridge in the United Kingdom had enough genomic data to test both models.

The classical analysis proceeds by evaluating repeated short DNA sequences (microsatellites) in order to compare samples from different organisms.

3 ′ - UTR poly (T / U) repeat of EWSR1 is altered in microsatellite unstable colorectal cancer with nearly perfect sensitivity.

For the remaining 14 samples, a match was nearly perfect, with only one or two of the microsatellite markers varying, typically by only one repeat unit, as might be expected through microsatellite instability within a pedigree.