DK synthesized and functionalized the nanoparticles, performed confocal
microscopy studies and co-wrote the manuscript.
Our microscopy studies at high magnification and high resolution have revealed a clear segregation between Aβ - immunoreactivity and that of APP and its C - terminal fragments (CTFs).
Our microscopy studies with quantitative co-localization analysis revealed the presence of intraneuronal Aβ in transgenic rats, with an immunological signal that was clearly distinguished from that of the amyloid precursor protein (APP) and its C - terminal fragments (CTFs).
We will then perform
microscopy studies on the same brains and align the two sets of images.
Sponsors: Research supported by the U.S. Department of Energy's Office of Science, Basic Energy Sciences (atomic force
microscopy studies), the Pacific Northwest National Laboratory Laboratory Directed Research and Development effort (peptoid synthesis), and the China Scholarship Council (FJ).
In situ atomic force
microscopy studies and molecular dynamics simulations were supported by the U.S. Department of Energy (DOE), Office of Science, Office of Basic Energy Sciences, Biomolecular Materials Program at PNNL.
«These fluorescence
microscopy studies establish that the zinc spark occurs in human egg biology, and that can be observed outside of the cell,» said Professor Tom O'Halloran, a co-senior author and director of Northwestern University's Chemistry of Life Processes Institute, of a study that appeared in Scientific Reports.
«Electron -
microscopy studies from back in the 1960s show depressions in the yeast membrane, but they were not studied in detail and were dismissed as artefacts of sample preparation», explains University of Groningen Professor of Biochemistry Bert Poolman.
«We also managed to confirm observations from previous
microscopy studies that suggested that cellular regeneration shares similarities with the process of cell division.
Montgomery's data set would make her paper strong, logical, and publishable, and the antibody would be useful for important
microscopy studies.
We present a cryo — electron
microscopy study at ∼ 13 to 15 angstroms of the entry of tmRNA into the ribosome.
V. Cassina, D. Seruggia, G. L. Beretta, D. Salerno, D. Brogioli, S. Manzini, F. Zunino and F. Mantegazza «Atomic force
microscopy study of DNA conformation in the presence of drugs» European Biophysics Journal, 40, 59 - 68, (2010) 4.
Learn through group discussions and personalized
microscopy study.
Not exact matches
For the current
study, working in the CU Cancer Center Advanced Light
Microscopy Core, co-authors Dominik Stitch, PhD, and Radu Moldovan, PhD, implemented a new technique known intravital multiphoton in vivo
microscopy that enabled the team to watch fluorescent - tagged liposomes in real - time after injection.
This new development paves the way for a new field of dynamical
study in the position dependence of atomic vibration in small particles, and is also likely to benefit the catalytical
study of particles.Richard Aveyard, Postdoctoral Research Associate in the Department of Physics at York, said: «Our work highlights the valuable contribution that computational simulations can have in the field of electron
microscopy: the more details we can put into our simulations, the more details we can extract from experiments.»
He
studies DNA and RNA quadruplexes, nucleic acid structures that were first visualized via confocal
microscopy in fixed, dead cells.
The latest in live - cell
microscopy — multiphoton imaging, light - sheet techniques, and technology borrowed from Raman spectroscopy — allow researchers to
study living cells in more detail with less effort.
Efficient collection and detection of fluorescence coupled with careful minimization of background from impurities and Raman scattering now enable routine optical
microscopy and
study of single molecules in complex condensed matter environments.
«Moving to non-invasive and repeatable methods of nerve fiber measurements such as in vivo corneal confocal
microscopy would enhance
study of peripheral neuropathy by enabling early detection of damage, progression of nerve fiber deterioration, and enable assessment of therapeutic strategies in the SIV / macaque model,» explains Dr. Mankowski.
Studies have shown that corneal nerve fiber density, measured by confocal
microscopy, can predict diabetes - related damage to the peripheral nerves, called peripheral neuropathy.
Room - temperature investigations apply several techniques (polarization
microscopy, single - molecule imaging, emission time dependence, energy transfer, lifetime
studies, and the like) to a growing array of biophysical problems where new insight may be gained from direct observations of hidden static and dynamic inhomogeneity.
Eric Betzig, Stefan W. Hell and William E. Moerner share the 2014 chemistry Nobel for the development of super-resolved fluorescence
microscopy, which has enabled the
study of single molecules in ongoing chemical reactions in living cells.
The dissociation of nitric oxide on a ruthenium (0001) surface was
studied by scanning tunneling
microscopy.
Study co-author Dr Carolina Loch says this was the first time the enamel ultrastructure of fur seals and sea lions, as well as the extinct walrus Pelagiarctos, was
studied using scanning electron
microscopy.
It builds upon previous
studies by Ozcan's group that used deep learning to reconstruct holograms and improve
microscopy.
«Understanding how the enzyme actually works requires the knowledge of its three dimensional molecular structure at the atomic level,» said Dr. Mueller, principal investigator for the
study that used cryo - electron
microscopy (cryo - EM) to reveal the enzyme at near atomic resolution.
«We use a technique called scanning X-ray fluorescence
microscopy,»
study co-author Satoshi Matsuyama says.
Our
study demonstrates the emerging ability of optical
microscopy to investigate intracellular physiological processes on the nanoscale in real time.
The recent
study, which was produced primarily through a research partnership between the University of Arkansas, Missouri State University and the University of Antwerp in Belgium, consisted of high - resolution transmission electron
microscopy combined with scanning tunneling
microscopy and state - of - the - art computational molecular dynamics.
The researchers
studied nanowires using X-ray
microscopy and with this method they can pinpoint exactly how the nanowire should be designed to give the best properties.
On a
study funded by the National Science Foundation and Agilent Technologies, researchers employed spatial light interference
microscopy (SLIM), a label - free method, to perform localized measurements of light scattering in prostatectomy tissue microarrays.
The researchers
studied the diamond samples using a combination of advanced transmission electron
microscopy techniques at EPFL's Interdisciplinary Centre for Electron
Microscopy.
To better determine the role of specific chemoattractants in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's lab, used multiphoton intravital
microscopy — an imaging technology pioneered for
studies of immune cell movements in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow in real time the development of IC - induced arthritis in a mouse model of rheumatoid arthritis.
But X-ray
microscopy can image a larger field of view and thicker materials than TEM, meaning it can
study materials that more closely resemble real - world batteries.
Previously, Chueh and other scientists have used transmission electron
microscopy (TEM) to
study working batteries at the nanoscale.
To carry out the
study, the team visualised a number of motors from different species of bacteria using a variant of a method called cryo - election
microscopy, whose pioneers were awarded the Nobel Prize in Chemistry this year.
Backman has been
studying cell abnormalities at the nanoscale in many different types of cancers, using an optical technique he pioneered called partial wave spectroscopic (PWS)
microscopy.
The structure of RuO2 (110) and the mechanism for catalytic carbon monoxide oxidation on this surface were
studied by low - energy electron diffraction, scanning tunneling
microscopy, and density - functional calculations.
Automated image analysis enables
studies that would be difficult or impossible with traditional
microscopy.
The research involved the
study of laboratory earthquakes — high - pressure earthquakes as well as high - speed ones — using electron
microscopy in friction and faulting experiments.
Described in a
study published in the journal Nature Communications, this novel approach uses high - speed atomic force
microscopy (AFM) combined with a CRISPR - based chemical barcoding technique to map DNA nearly as accurately as DNA sequencing while processing large sections of the genome at a much faster rate.
«We
studied a range of authentic microfossils using the same transmission electron
microscopy technique and in all cases these reveal coherent, rounded envelopes of carbon having dimensions consistent with their origin from cell walls and sheaths.
Dr. Taraska's lab
studies the structural cell biology of exocytosis and endocytosis with advanced imaging methods including live cell
microscopy, superresolution fluorescence, and electron
microscopy.
Scientists usually
study them visually and using data; with modern
microscopy it is possible to directly see the structure of some proteins.
You will also hear case
studies about how superresolution
microscopy data has made the difference between acceptance and rejection of key papers by scientific journals.
Using transmission electron
microscopy imaging and powder X-ray diffraction to
study the structural characteristics of the nanoparticles and Raman and photoluminescence spectroscopies to quantify lattice strain and photoluminescence behavior, the group found a correlation between the amount of tin in the core and how well the core's lattice matched that of the cadmium - sulfide outer shell.
A change of research focus to microbiology led to a burgeoning interest in optical
microscopy and its application to the
study of biofilms and motility in bacteria.
The catalytic oxidation of carbon monoxide (CO) on a platinum (111) surface was
studied by scanning tunneling
microscopy.
Another potential use for this material, besides photovoltaics, is that in
microscopy or imaging, researchers often need to «label» a protein or other feature with a nanoparticle «probe» to make it light up so it is easier to see and
study.
I had completed a postdoc with Prof. Michael Rossmann during which I
studied virus - receptor relationships by using x-ray crystallography and electron
microscopy.