Sentences with phrase «microstimulation in»

Thank you for submitting your article «Theta - burst microstimulation in the human entorhinal area improves memory specificity» for consideration by eLife.

Future work examining the physiological effects of microstimulation in downstream regions, such as the hippocampus, would further enlighten the mechanisms of the differential effects when stimulation is applied in gray matter or the angular bundle.

Theta - burst microstimulation in the human entorhinal area improves memory specificity.

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Tactile percepts were consistently elicited in the hand of a person with cervical spinal cord injury using intracortical microstimulation of the somatosensory cortex.

This study presents the first evidence that microstimulation has the potential to improve hippocampal - dependent memory in humans.

In conclusion, our findings suggest that microstimulation, with its anatomical precision, physiologic - level currents, and action via axonal projections, holds promise for modification of memory circuits and thus for the treatment of memory impairments in people suffering from neurological disorderIn conclusion, our findings suggest that microstimulation, with its anatomical precision, physiologic - level currents, and action via axonal projections, holds promise for modification of memory circuits and thus for the treatment of memory impairments in people suffering from neurological disorderin people suffering from neurological disorders.

Future studies investigating how neural signals change in response to microstimulation (and how these changes vary with the precise targeting of the stimulating electrode) will be critical for increasing our understanding, not only of the physiological signatures of microstimulation, but also the microcircuit dynamics underlying memory.

As thirteen neurosurgical patients performed a person recognition task, microstimulation was applied in a theta - burst pattern, shown to optimally induce LTP.

We therefore hypothesized that theta - burst microstimulation, targeted to brain regions containing afferent fibers to the hippocampus, would improve episodic memory performance in humans.

Importantly, LTP induction by high - frequency microstimulation of the perforant path in vivo has been shown to cause reorganization of wide hippocampal and cortical networks in rats (Canals et al., 2009).

Here, we asked whether application of microstimulation targeted to the entorhinal afferents into hippocampus could enhance declarative memory function in humans.

This method could potentially have many advantages over the macroelectrode stimulation used in previous studies as microstimulation is much more spatially focused and uses currents on a more physiologic level.

Further research is needed to elucidate the mechanisms that shape the spatial - temporal firing patterns during saccades, and the behavior of the SC population in more complex motor behaviors, like during head - free gaze shifts, curved double - step saccades, or electrical microstimulation.