Sentences with phrase «microvascular endothelial cells»

The researchers used human umbilical vein endothelial cells and human microvascular endothelial cells for the study.

Increased MAPK activation and impaired insulin signaling in subcutaneous microvascular endothelial cells in type 2 diabetes: the role of endothelin - 1

Rab1 GTPase promotes expression of β - adrenergic receptors in rat pulmonary microvascular endothelial cells.

HIF - 2α expression regulates sprout formation into 3D fibrin matrices in prolonged hypoxia in human microvascular endothelial cells.

Specific inhibition of AQP1 water channels in human pulmonary microvascular endothelial cells by small interfering RNAs.

Hyperosmolarity attenuates TNF - α — mediated proinflammatory activation of human pulmonary microvascular endothelial cells.

The immortalized mouse brain microvascular endothelial cells (mBrEC) were supplied by Dr. Isaiah J. Fidler (M.D. Anderson Cancer Center, Houston, TX; ref.

One of the primary objectives of this study was to establish a protocol to facilitate the identification and selection of microvascular endothelial cells from primary organ cultures with a high degree of precision.

A, comparison of E-selectin expression in control colon (top left panel) to TNF - α - stimulated expression in colon (center panel) and ovarian (right panel) microvascular endothelial cells.

We capitalized on one of the innate responses of microvascular endothelial cells, i.e., the up - regulation of cell adhesion molecules in response to inflammatory agents, to generate endothelial cell lines from different organs.

This latter observation adds to the expanding body of evidence indicating that brain microvascular endothelial cells lack receptors for chemically modified LDL (27, 28).

To overcome these limitations, we used two - color flow cytometry to identify and select microvascular endothelial cells from primary cultures obtained from different organs of mice whose tissues harbor a temperature - sensitive SV40 large T antigen (H - 2Kb - tsA58 mice; ImmortoMice).

The epithelium's maturation into a villus intestinal epithelium with long finger - like extensions was helped along by co-culturing human intestinal microvascular endothelial cells on the opposite side of the shared matrix - coated porous membrane in the «vascular» channel where they assembled a surrogate blood vessel with a hollow lumen through which feeding medium was flowed.

Specifically, the study — reported online in The Journal of Infectious Diseases — shows that E. coli K1 modulates the protein peroxisome proliferator - activated receptor - gamma (PPAR - γ) and glucose transporter - 1 (GLUT - 1) levels at the blood - brain barrier in human brain microvascular endothelial cells.

Tissue - specific microvascular endothelial cell lines from H - 2K (b)- tsA58 mice for studies of angiogenesis and metastasis

The selection strategy targeted cell populations expressing the inducible endothelial cell adhesion molecules, E-selectin and VCAM - 1, and proved successful in generating microvascular endothelial cell lines from a number of different organs.

Not exact matches

To determine whether endothelial cells — the cells that line the interior surface of blood vessels — directly influence breast cancer cell growth, they then created unique organotypic models of lung and bone marrow microvascular niches, in which endothelial cells formed blood vessel - like structures in culture as they would in the original organ.

From these cell based and clinical studies, we have developed important mechanistic ideas such as activation of protein kinase C, the role of vascular endothelial growth factor (VEGF) and selective insulin resistance as some of the basic mechanisms for the pathogenesis of diabetic microvascular and cardiovascular diseases which are now widely studied by multiple laboratories.