Sentences with phrase «microvasculature of»

Scanning electron micrograph of the coronary microvasculature of a mouse that has been treated with a small molecule tyrosine kinase inhibitor of platelet - derived growth factor receptor beta.

And the work of Landon King, who is the director of the pulmonary and critical care medicine program at Johns Hopkins now; when Landon was a fellow in our laboratory, he discovered that in fact glucocorticoids, corticosteroids induce regulation expression of the aquaporins in the microvasculature of the lung.

To test this idea, the researchers utilized two mouse models of human breast cancer metastasis and found dormant disseminated tumor cells residing upon the membrane microvasculature of lung, bone marrow and brain tissue.

Not exact matches

The tiny sensors, which consist of infrared light - emitting diodes (LEDs) coupled with a sensitive light detector, measure infinitesimal gradations in light in human tissue, due to changing blood volume in the microvasculature as blood circulates through the body — a process that follows in rhythm with the beating of the heart.

Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) have identified the microenvironment surrounding microvasculature — the small blood vessels that transport blood within tissues — as a niche where dormant cancer cells reside.

The identification of dormant niches in basement membrane microvasculature and how those niches become metastatic in the neovasculature holds important implications for future breast cancer therapies.

Given that breast cancer cells traveling through the bloodstream on their way to secondary sites where breast tumors metastasize most often — lung, bone marrow, brain and liver — must first pass through the basement membrane microvasculature, Ghajar and Bissell suspected that the basement membrane could be a major component of the dormant niche in distant organs.

Megakaryocytes — some of which were derived from patients — were seeded into the engineered microvasculature.

How hemostatic thrombi limit the loss of plasma - borne molecules from the microvasculature.

Yet, pericyte coverage in resting vessels varies widely in different organs and with type of microvasculature (continuous versus discontinuous versus fenestrated).

Improving our understanding of the relationship between changes in the retinal microvasculature, RNFL and lamina cribrosa in the pathophysiology of glaucoma can inform the development of new therapeutic targets designed to slow the microvasculature changes as a new non-IOP lowering approach to glaucoma therapy.

Moreover, this study will determine whether changes in retinal microvasculature can be used as a biomarker or clinical indicator for monitoring progression of glaucoma in clinical practice.

A transcriptome research of its organs revealed its gene signature is highly evolved and adapted for extreme longevity (slow metabolism, improved insulin gene signaling and glucose homeostasis, thus reduced blood glucose, improved cancer genes, improved endothelial function by eNOS (endothelial Nitric Oxide Synthase) meaning improved vascular coronary blood flow, improved microvasculature arterial and heart endothelium function) but more importantly, to answer your question, some whales display low blood glucose hypoglycemia, this affects the quantity and period of proteins / DNA / cell exposure to glucose glycation, glycosylation and glycoxydation reactions.

Chairs: Elena Aikawa, Brigham and Women's Hospital / Harvard Medical School and Anjelica Gonzalez, Yale University Christopher Hughes, University of California, Irvine Vascularized and perfused micro-tissues in culture and their use in drug screening Ying Zheng, University of Washington Engineering organ - specific microvasculature

The two main causes of malaria, P. falciparum and P. vivax, differ in their ability to cause severe disease, mainly due to differences in the cytoadhesion of infected erythrocytes (IE) in the microvasculature.

The effects of magnetic field exposure on blood flow and blood vessels in the microvasculature.

Cinnamon can also act as an agent that can increase circulation - which is highly beneficial to allow the immune system to reach the very small blood vessels (microvasculature) of the affected lung tissue.