Sentences with phrase «migrating cells»

Methods: The PNNL team applied global proteome profiling in combination with UCSD - developed phosphoproteomics approaches to understand signal organization in migrating cells.

These are some of the fastest migrating cells in the human body, and they are the first responders at damaged locations or areas of infection and begin the process of healing.

This process requires a fundamental change in the character of cells within the primary tumor, insofar as members of a localized cell mass must be converted into actively migrating cells that invade into the surrounding tissue and blood vessels, and finally settle in distant tissues.

As more and more studies deliver results showing activity similar to that of Friedl's migrating cell clusters, however, researchers have begun to question whether go - it - alone mesenchymal cells, which Friedl calls «lonely riders,» could really be the main culprits behind the metastatic disease that kills millions.

Numbers of migrating cells, shown in red, are greatly reduced when the molecule FOX01 is deleted (right column).

Not only do birds flock together but so too do countless examples throughout life, from the macroscopic to the microscopic, including schools of fish, colonies of bacteria, groups of migrating cells and even some proteins.

Migrating cells are known to form dynamic protrusions at their leading edge, but the function of these actin - rich protrusions has remained elusive.

The technique offered precise localization of dynamic microtubule plus - end hub protein EB1 dimers, and their distinct distributions at the leading edge and cell body of migrating cells, the researchers report.

In 3D matrices, even though the whole surface of a migrating cell is available for interacting with the ECM, it is unclear whether discrete adhesion structures actually exist.

In 2D, only the ventral surface of a migrating cell is in contact with the ECM, where cell - matrix adhesions are assembled.

After 4 h, the number of migrated cells was quantified using a Guava EasyCyte flow cytometer.

Migrated cells were counted by flow cytometry using 6.0 - μm Fluoscribe microspheres (Polysciences, Warrington, PA).

Migrated cells were stained with crystal violet and photographed.