Compared with unheated mice, the animals with the faux fever had twice as many white blood cells
migrating out of the blood vessels and into the lymph tissue that lines the skin and gut, which is where they need to be to attack incoming pathogens.
By masking JAM - C, H225 was able to prevent the cells from
migrating out of the blood vessels.
Not exact matches
A sleep deficit
of just four hours affects by as much as 50 percent the ability
of stem cells
of the
blood and immune system to
migrate to the proper spots in the bone marrow
of recipient mice and churn
out the cell types necessary to reconstitute a damaged immune system, the researchers found.
This triggers the development
of cholera - specific antibody secreting cells (ASCs) which transiently
migrate out of the gut and into the
blood circulation.