The laboratory currently pursues four integrated research objectives: 1) Defining how dynamic regulation of adhesion and
migration controls metastasis, 2) Identification and characterization of the metastatic cell populations within a primary tumor, 3) Experimental modeling of metastasis in a clinically relevant manner, and 4) clinical implementation of molecular markers of migration as biomarkers of tumor progression and metastasis.
The scientists hope their findings on cell
migration in zebrafish will open up new perspectives for research on proteins that
control metastasis and thus the malignancy of cancer.