Sentences with phrase «migration of cancer cells in»
Moreover, mebendazole inhibited invasion and migration of cancer cells in vitro, and formation of metastases in vivo in experimental animals.
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In the same way, observing the migration of cancer cells in a 3 - D environment could unlock information on how cancer grows, finds nutrients, and spreads.
Not exact matches
The scientists hope their findings on cell migration in zebrafish will open up new perspectives for research on proteins that control metastasis and thus the malignancy of cancer.
Adding two blood - borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Instcancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Instcancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer InstCancer Center reports in the Journal of the National Cancer InstCancer Institute.
This study, published in the journal Microarrays, shows that lack of SOST in the bone microenvironment promotes the expression of many genes associated with cell migration and / or invasion, including long non-coding RNA MALAT1 in prostate cancer, suggesting that SOST has an inhibitory effect on prostate cancer invasion.
New research shows that microRNA - 486 is a potent tumor - suppressor molecule in lung cancer, and that the it helps regulate the proliferation and migration of lung - cancer cells, and the induction of programmed cell death, or apoptosis, in those cells.
To test this idea, they experimentally reduced the expression of the DNM30S lncRNA, which resulted in reduced ovarian cancer cell migration and invasion.
More importantly, the fibronectin part of the complex is expressed during a cell's transition to cancer and plays a role in cell growth, migration and differentiation.
Recently published in the journal eLife and featured in a poster session at this year's American Association for Cancer Research (AACR) annual meeting, preclinical experiments show for the first time that PLK1 promotes the migration of prostate cancer cells by setting in motion a process that induces what is known as the epithelial - to - mesenchymal transition Cancer Research (AACR) annual meeting, preclinical experiments show for the first time that PLK1 promotes the migration of prostate cancer cells by setting in motion a process that induces what is known as the epithelial - to - mesenchymal transition cancer cells by setting in motion a process that induces what is known as the epithelial - to - mesenchymal transition (EMT).
They also play important roles in cell migration, regeneration, neurodegenerative diseases and the development of cancer.
A team of researchers at the Massachusetts General Hospital and Harvard Medical School in Boston has developed technologies for precision measurement of cell migration speed before and applied the new tool to study the variations of migration speed in population of cancer cells.
These kinds of experiments can be useful in investigating wound - healing processes or the migration of cells in cancer.
«In this study, we found that enhanced neuropilin - 1 (NRP - 1) and NEDD9 levels in endometrial and lung cancer positively correlated with metastasis, while liver kinase B1 (LKB1) inhibited the migration of cancer cells.&raquIn this study, we found that enhanced neuropilin - 1 (NRP - 1) and NEDD9 levels in endometrial and lung cancer positively correlated with metastasis, while liver kinase B1 (LKB1) inhibited the migration of cancer cells.&raquin endometrial and lung cancer positively correlated with metastasis, while liver kinase B1 (LKB1) inhibited the migration of cancer cells.»
SAP domain - dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients.
May 12, 2016 Stopping cancer in its tracks Researchers from the University of Chicago have shown that inhibiting autophagy, a self - devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models.
Small Cell Lung Cancer (SCLC): Overexpression of CXCR4 is found in SCLC [30, 31, 37] and mediates the migration of SCLC to bone marrow along an SDF - 1 gradient [37].
The role of tyrosine phosphorylated caveolin - 1 in regulating focal adhesion dynamics and cancer cell migration.
Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion.
In addition, the organs and tissues that possess high levels of SDF - 1, such as liver, lung, bone marrow, and lymph nodes, attract the migration of CXCR4 - expressing cancer cells [22].
Cancer, the uncontrolled growth and migration of a small population of cells within a given tissue, is one of the leading causes of death in the United States in older adults.
Our insight will substantially enhance our understanding of dynamic cell shape regulation for instance in the context of cell migration as in cancer metastasis or during morphogenesis.
Cancer cells in intravital mouse models and in vitro display many «modes» of migration, from single isolated cells with round or elongated phenotypes to loosely - / non-adherent «streams» of cells or collective migration of cell strands and sheets.
Forced expression of fascin1 in colorectal cancer cells increased their migration and invasion in cell cultures and caused cell dissemination and metastasis in vivo, whereas suppression of fascin1 expression by small interfering RNA reduces cell invasion.
In co-culture experiments on coated transfilters, both NAFs and CAFs induced migration and invasion of HT29, which are intrinsically noninvasive colon cancer cells.
Multiple studies have shown that fascin, through its role in formation of cellular protrusions such as filopodia and invadopodia, enhances cancer cell migration and invasion in vitro.
A «WOW» maple syrup finding: Take this 2015 study reported in Oncology Reports: the researchers examined the effect of three grades of maple syrup (grades are based on the color of the syrup and ranges from light to darker with color being influenced by time of year and processing technique) on the proliferation, migration, and invasion of colorectal cancer (CRC) cells in order to investigate whether maple syrup is suitable as a phytomedicine for cancer treatment.