An excessive intake of
caffeine can cause restlessness,
mild tachycardia, anxiety, or inability to sleep; all of these symptoms will disappear once
caffeine consumption is stopped or diminished.
To minimize this bias, we excluded at baseline 10 280 women with severe depressive symptoms and we computed the cumulative mean of caffeinated and noncaffeinated beverages with at least a 2 - year latency; yet, we can not exclude the possibility that
mild depressive symptoms were the common reason for low
caffeine consumption and incident depression.