He and other researchers will now use TRN manipulation in mice whose brains
mimic human disorders.
Not exact matches
This same shift has been observed in
human inflammatory
disorders, though previous attempts to
mimic it in lower organisms like fruit flies or zebrafish have proved unsuccessful.
Mutations in a gene called progranulin (GRN) are commonly associated with frontotemporal dementia, but GRN mutations in mice do not
mimic all the features of the
human disorder, which has limited progress in the development of effective treatments.
Rather than artificially triggering cancer by engineering genetic mutations, this model more closely
mimics human liver cancer in that tumors develop as a natural consequence of non-alcoholic steatohepatitis (NASH), a chronic metabolic
disorder that causes liver damage, fibrosis and numerous cell mutations.
«Having one that seems to
mimic the
disorder so well, especially in terms of the time course of treatments that work in
humans, is potentially very useful for researching novel therapeutics.»
Your cat's behavior may
mimic obsessive - compulsive
disorder in
humans.