The 3D structure of the pellet
mimics embryonic development of the limbs, and improves the intercellular communication essential for chondrogenesis to occur [8, 9].
They then exposed these cells to certain growth factors in - vitro to cause them to turn into liver - like cells, in a process that
mimics embryonic development.
«That was what was different in this particular study, we created a differentiation protocol to
mimic embryonic development.»
Salk scientists and colleagues have proposed new molecular criteria for judging just how close any line of laboratory - generated stem cells comes to
mimicking embryonic cells seen in the very earliest stages of human development, known as naïve stem cells.
One is the molecular identification of cell growth and differentiation factors, and their receptors that
mimic embryonic developmental cues, and allow PSCs to differentiate into almost any mammalian cell type.
Not exact matches
We also observed a low frequency of a variety of
embryonic defects in the experimental groups, such as neural tube, heart looping, and turning defects; these results
mimic the low incidence and multifactorial nature of these anomalies in humans.
Now, a collaborative team of scientists at Washington University in St. Louis has developed a new process to generate NP - like cells from hiPSCs, one that truly goes back to the beginning and
mimics the process of
embryonic development.
Yamanaka's group and two others followed up earlier this year with firmer evidence that these induced pluripotent stem (iPS) cells faithfully
mimicked the patterns of gene activity and cellular differentiation observed in
embryonic stem cells.
Instead of
mimicking the complex 3D organization of the developing pituitary gland, this approach relies on the precisely timed exposure of human pluripotent stem cells to a few specific cellular signals that are known to play an important role during
embryonic development.
When current methods for generating naïve stem cells in the lab were judged using the three tests, each fell short of
mimicking the naïve
embryonic cells in different ways.
Veronica Palma, from University of Chile, led the study with Rehen and highlights the combined approaches allowed the creation of an environment that
mimics the one during
embryonic brain development.
Now researchers have found a way to create stem cells that
mimic the universal role of
embryonic cells.
This reprogramming methodology dispenses with the standard nucleic acid - mediated strategy and instead treats cells with conditioned media (CM) designed to
mimic the primitive
embryonic environment.
By: Sadhana Agarwal, Katherine L. Holton, Robert Lanza Differentiation of human
embryonic stem cells (hESCs) to specific functional cell types can be achieved using methods that
mimic in vivo
embryonic developmental programs.
Since human
embryonic stem cells grow in an adherent culture system, for cells being reprogrammed this «new culture system» is an adherent culture system (to try and
mimic the conditions the
embryonic stem cells want to be happy).
But the eyebrow - raising reports claimed that adult stem cells sometimes behave like their
embryonic counterparts,
mimicking their trademark capacity to engender all types of cells — an ability dubbed pluripotency.
«Importantly, we have achieved our insights by
mimicking molecular processes occurring during
embryonic cartilage formation,» says Ivan Martin.
Researchers announced they
mimicked the way
embryonic stem cells develop into heart muscle in a lab.
Virginia Commonwealth University (VCU), Richmond • VA 2008 — 2008 Experiment Design, Project Innovatively designed an experiment that would utilize
embryonic stem cells, and scaffold to
mimic kidney function.