Rather than artificially triggering cancer by engineering genetic mutations, this model more closely
mimics human liver cancer in that tumors develop as a natural consequence of non-alcoholic steatohepatitis (NASH), a chronic metabolic disorder that causes liver damage, fibrosis and numerous cell mutations.
Not exact matches
In research published in Molecular Cell, Rutgers scientists discovered that a protein (p62), which is supposed to act as an antioxidant to prevent cell damage, was not working efficiently in laboratory mice with
liver and heart disease that
mimicked these conditions in
humans.
To determine the effect of gastric acid suppression on the progression of chronic
liver disease, Schnabl's team looked at mouse models that
mimic alcoholic
liver disease, NAFLD and NASH in
humans.
«Bioengineered
human livers mimic natural development: Study uncovers previously unknown genetic - molecular crosstalk.»