TSI is directly correlated with sunspot
numbers, and the long and deep solar
minimum we just came through where the sun was blank for long periods
of time would necessarily mean that TSI was also lower for an extended period
of time This is not what the
measurements show.
Given the primary objectives
of the trial and measures collected in existing RCTs, 18, 49 we chose to anchor our sample size calculation around detection
of a
minimum effect size
of 0.3 for the responsivity subscale
of the Home Observation
Measurement of the Environment (HOME) Inventory (see table 2), to allow comparisons with the original MECSH trial and other international SNHV programmes.60 The sample size applies across all
of the subscales
of the HOME Inventory and other continuous outcomes as based on
number of SDs rather than the actual outcome distributions.