Not exact matches
Fishel and Kolodner had been studying the bacteria and yeast genes involved in the repair process that operates when
base pairs slip out of alignment during replication, producing
mismatches of
bases.
«A difference in just a single
base pair can cause a decrease in binding efficiency due to a
mismatch with the guide RNA.
The probe has a weak response to
mismatch - containing dsRNA sequences, thus enabling sequence - selective fluorescence sensing of dsRNA at the single -
base pair resolution.
The DNA fragments from ancient specimens do not overlap perfectly due to degradation of the DNA code, causing
mismatches in
base pairs that were originally the same — these are «false mutations».
Pete Doherty and Charlotte Gainsbourg make a
mismatched pair in a flat drama
based on a 19th - century novel, writes Philip French