Sentences with phrase «mitochondria after fertilization»
But that could not explain why certain genetic markers related to autophagy were still detected on the paternal mitochondria after fertilization.
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After the woman's eggs have been retrieved through the normal IVF protocol and are ready for fertilization, the mitochondria taken from her stem cells are injected into an egg along with a sperm cell.
(Sperm have mitochondria, but they are thought to degrade shortly after fertilization.)
Shortly after a sperm penetrates an egg during fertilization, the sperm's mitochondria are degraded while the egg's mitochondria persist.
(Although sperm have mitochondria, they typically degrade shortly after fertilization.)
A few research groups around the world have experimented with ways to transfer the genetic material from an egg with faulty mitochondria into a healthy egg, either before or just after fertilization.
Moreover, because mitochondria are only inherited from mothers, the DNA is not subject to the gene shuffling that affects the rest of the genome after fertilization.
Although the probability is very low, the take home message is that for clinical purposes, we should focus on the transfer of single spindle or a polar body, which would carry less mitochondria than the standard transfer of two pronuclei after fertilization.