Not exact matches
It was found that complex II activity significantly declined with age, per unit of
mitochondria, in the
cells derived from the lower rather than the upper levels, an observation not previously reported
for human skin.
Residing in large numbers outside the nucleus of every
cell,
mitochondria contain their own DNA, with unique features that «may require a reassessment of some of our core assumptions about
human genetics and evolutionary theory,» concludes Wallace, director of the Center
for Mitochondrial and Epigenomic Medicine at The Children's Hospital of Philadelphia.
Human mitochondria,
for example, have just 13 genes that code
for proteins of their own but employ thousands of proteins in their quest to make energy
for the
cell.
«The introduction of
mitochondria into damaged
cells has beneficial effects on the health of
cells and, in the long term, we believe that mesenchymal stem
cells could even be engineered to create more effective therapies
for lung disease in
humans.»
Aug 8, 2008 Two New Predisposition Genes
For Breast, Thyroid And Kidney Cancers Could Lead to More Accurate Diagnosis and Earlier Detection of These Cancers Charis Eng, MD, PhD, Sondra J and Stephen R Hardis Endowed Chair of Cancer Genomic Medicine and Chair, GMI, and her team published in the Aug 8, 2008 issue of the American Journal of
Human Genetics that germline mutations in SDHB and SDHD, which play key roles in the
mitochondria (the
cell's power houses), predispose to Cowden and Cowden - like syndromes.
Mitochondrial biogenesis is the ability to promote the spontaneous generation of new
mitochondria within aging
cells, and it's the closest thing yet discovered to a «fountain of youth»
for human beings.