Sentences with phrase «mitochondrial iron uptake»
«Our results demonstrate,» the researchers say, «the importance of mitochondrial iron uptake in trypanosomatid parasites, and highlight the role of LMIT1 in the iron - regulated process that orchestrates differentiation of Leishmania amazoniensis into infective amastigotes.»
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They add, that «by identifying and characterizing LMIT1 as a mitochondrial iron importer, we established a direct connection between iron uptake, mitochondrial redox balance and the development of virulence in Leishmania, significantly expanding future options for controlling these serious human infections.»