Sentences with phrase «mitochondrial pathway»

The Warburg Effect refers to the fact that cancer cells, somewhat counter intuitively, prefers fermentation as a source of energy rather than the more efficient mitochondrial pathway of oxidative phosphorylation -LSB-...]

The Warburg Effect refers to the fact that cancer cells, somewhat counter intuitively, prefers fermentation as a source of energy rather than the more efficient mitochondrial pathway of oxidative phosphorylation (OxPhos).

«Subsequent experiments revealed that mensacarcin rapidly alters mitochondrial pathways, resulting in mitochondrial dysfunction.»

By blending classic biochemistry, molecular & cellular biology, and bioenergetics with large - scale proteomics and systems approaches, our lab aims to systematically annotate the functions of uncharacterized mitochondrial proteins (MXPs) and to establish the detailed mechanisms that drive essential mitochondrial pathways.

The mitochondrial pathway of cell death (apoptosis) starts by permeabilization of the mitochondrial outer membrane which becomes peppered with small holes.

Mammalian cells treated with Mcf1 also display key features of apoptosis which is putatively mediated by a BH3 - like domain and involves the mitochondrial pathway [24], [25].

We recently identified a candidate protein sensor for ceramides and found that acute disruption of sensor function causes a rise in ER ceramides and their mislocalization to mitochondria, triggering a mitochondrial pathway of apoptosis.

The mitochondrial pathway.

While capsaicin affected the mitochondrial pathway of the cancer cells, there was no interference in the activity of healthy cells.