Despite remarkable improvement in the generation of hPSC - CMs, without purification, these protocols can only generate
mixed cell populations including undifferentiated hPSCs or non-CMs, which may elicit adverse outcomes.
The periosteum is
a mixed cell population of fibroblasts, osteoblasts, MSCs, and pericytes cells.
Not exact matches
They might also come up with a way to select the right
cells out of a
mixed population; Anand Swaroop, an ophthalmology researcher at the University of Michigan at Ann Arbor, is working on a way to identify and weed out the photoreceptor
cells by focusing on proteins present on
cell surfaces.
Reporting their laboratory findings in the journal Aging, the team observed that addition of DPI to a
mixed population of
cells eliminated the tumour initiating cancer stem
cells.
However, due to technological limitations, previous genetic studies largely focused on
mixed populations of
cells, obscuring critical nuances in cellular behavior.
Other forms of
cell -
cell interaction, on the other hand, are only effective in
mixed population structures; these include, for example, cross-feeding mutualisms in which different
cell types depend on close proximity to benefit each other [17 — 19].
As an additional finding, we observed little stimulation of purified naive DGKζ - deficient CD8 + T
cells, relative to Cbl - b — deficient or DKO
cells (compare Fig. 3A with Fig. 3D), at limiting dilutions of anti-CD3 (0.3 μg / ml), when compared with DGKζ - deficient T
cells in a
mixed population.
This gave a
mixed population of
cells with 20 % expressing CD34, a hematopoietic stem
cell marker, with some co-expression of endothelial
cell markers (CD31, Flk1, and VE - cadherin).
Your fatty tissue is also home to a
mixed population of
cells which are able to secrete vital growth factors.
Using a
mixed lymphocyte
population obtained from a mucosal tissue (tonsils) we treated
cells with or without lethal toxin for 3 hr and then stimulated the
cells with or without IL - 23.
Moreover, all of these studies compare the pluripotent potential of the marked ICM - like
population to
mixed fractions that are considered a single further differentiated intermediate
cell type.
Our findings suggest that pluripotency is determined by the capacity of a
mixed population of lineage - biased intermediates to commit to different
cell fates in specific contexts.
This may reflect the
mixed population of germ
cells in the EBs, which was demonstrated by the immunostaining analysis.
These results may suggest that a
mixed population of ES
cells differentiating into germ
cells is present in monkey EBs.
The MID and LOW
populations gave rise to some of these stem
cell colonies, but formed more
mixed or abortive colonies that were partially positive for GCTM - 2 than did the HIGH or NEG fractions.
They may be the predominant
cell type on occasion, as in eosinophilic gastroenteritis, but they are more commonly part of a
mixed population of inflammatory
cells.