The same is true for the very
mixed results of studies about the effectiveness of TFA teachers compared to non-TFA teachers.
Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial
results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer
mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable
results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical
studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Although a number
of studies have investigated the evidence for anti-obesity programmes at school, the
results have been
mixed and the
studies weak.
Studies have yielded
mixed results, which may reflect
study design, such as how breastfeeding was defined, relying on recall
of feeding from prior years, and other factors.
Research on the impact
of depression on home visiting outcomes is
mixed with some
studies reporting negative
results while others suggesting that depressed mothers may benefit from these programs.
In other words, even when home visitation programs succeed in their goal
of changing parent behaviour, these changes do not appear to produce significantly better child outcomes.21, 22 One recent exception, however, was a
study of the Home Instruction Program for Preschool Youngsters (HIPPY) model with low - income Latino families showing changes in home parenting and better third - grade math achievement.23 Earlier evaluations
of HIPPY found
mixed results regarding program effectiveness.
Lay support has been associated with improved breastfeeding practices, but
studies of programs that engage men in breastfeeding support have shown
mixed results and most are from high - income countries.
As far as communication in climate policy is concerned, the
study's
results suggest that in future a comprehensive
mix of information on climate change and various justifications for climate protection will be necessary.
The
study plots were in California, but the authors suggest
study results could apply to
mixed conifer forests across the North American Mediterranean Climate Zone, which stretches from southwestern Oregon through California to northern Baja California and includes parts
of western Nevada.
The
study publishing January 9 in the open access journal PLOS Biology led by researchers from Uppsala University with an international team
of collaborators, also indicates that the
resulting mixed population genetically adapted to the extreme environmental conditions.
DeLaune said previous field
studies from the Rolling Plains and adjacent High Plains demonstrated
mixed results, with some showing a reduction in soil moisture and cash crop yield due to cover crops and others indicating no significant impact
of cover crops on subsequent fiber yield.
Geneticist Iosif Lazaridis
of Harvard Medical School in Boston, who
studies how and when ancient populations
mixed, calls the new
results «a big accomplishment.»
And a few
studies have found that women expend more energy in producing breast milk for boys — although the
results of such
studies have been
mixed.
But
studies of how this drastic change affected temperatures on land have had
mixed results.
In the review, the researchers noted the
mixed results of a total
of thirteen quantitative
studies investigating whether and how depression is associated with substance - related outcomes.
Previous
studies of their effectiveness in patients with end - stage renal disease produced
mixed results, leading researchers to conduct the review
of records
of all U.S. patients who had initiated peritoneal dialysis from 2007 to 2011.
However, determining just how, and by how much, has yielded
mixed results — not only because
of questions around the realism
of related
studies, but also because parsing the contributing impacts
of other threats to bees, such as climate change, has been difficult.
Of the 38 studies the authors surveyed, which were winnowed down from a pool of thousands, 14 favored Canada, five the U.S., and 19 yielded mixed result
Of the 38
studies the authors surveyed, which were winnowed down from a pool
of thousands, 14 favored Canada, five the U.S., and 19 yielded mixed result
of thousands, 14 favored Canada, five the U.S., and 19 yielded
mixed results.
However, the research team notes that previous
studies on associations between diet soda and risk
of type 2 diabetes have produced
mixed results, and further
studies are needed to reveal the long - term health impact
of artificially sweetened drinks.
«A number
of studies have looked at nutrition in patients with sepsis, and the
results have been
mixed.
Mixed results from
studies of primates suggest that caloric restriction may make monkeys healthier but doesn't prolong their lives (SN: 8/1/09, p. 8; SN: 10/6/12, p. 8).
Past
studies of high - fat diets have yielded somewhat
mixed results in rodents, says Ralph DiLeone, a neurobiologist at Yale University.
Although lab
study results on exercise levels after sleep deprivation have been
mixed, people generally report feeling more lethargic and less capable
of getting the recommended moderate - to high - intensity exercise.
Some Academy members are PhDs who
study HIV but can't prescribe medication, so survey
results were analyzed for only the subset
of members who can do so: mostly primary care providers, internal medicine, and infectious disease specialists who see a
mix of patients, some with the virus and some without it.
So researchers in the UK and US analysed the
results of over 90
studies (a
mix of randomised trials and cohort
studies)
of prenatal iron use and prenatal anemia, involving nearly two million women.
Most
studies on the effects
of brain - training games have been small and had
mixed results.
Earlier
studies have shown
mixed results, some
studies found slightly increased risk
of melanoma among sunscreen users.
The
results of LCPUFA supplementation
studies have been
mixed according to Colombo, a neuroscientist who specializes in the measurement
of early neurocognitive development, but many
of those
studies have relied mainly on children's performance on the Bayley Scales
of Infant Development at 18 months.
Results of previous
studies in mice
of bexarotene's effect on AD have been
mixed, and none
of those
studies were done in mice that carry a human APOE gene and also develop progressive, AD - like pathology.
«Our
results are a
mixed bag,» said lead author Matthew Luskin, who conducted the research for his graduate
studies at the University
of California, Berkeley, and is now a research fellow with the Smithsonian Institution and based at Nanyang Technological University in Singapore.
A
mix of perennial grasses and herbs might offer the best chance for the U.S. to produce a sustainable biofuel, according to the
results of a new
study.
Overall,
studies in the field indicate that children from low - income families tend to show the most gains from social emotional learning interventions, but
results for other groups
of students are more
mixed, although a number
of studies show positive effects.
Prior
studies examining how war may affect the HIV epidemic have produced
mixed, and even conflicting,
results, said senior author Mark Lurie, associate professor
of epidemiology in the Brown University School
of Public Health.
Catalase: Gene therapy to increase levels
of the antioxidant catalase in the mitochondria in mice have produced
mixed results, but some
studies show improved health and extended life.
The subsequent
studies have produced a
mixed bag
of results, with some showing higher methane emissions than expected, and others lower.
The same
mix of results held true for
studies looking into storms.
If you are over the age
of 50, one
study suggests that you can get the best
results from combining resistance and aerobic training, which could involve any type
of exercise ranging from HIIT (High - Intensity Interval Training), such as various circuit training sessions to dynamic yoga, which
mixes strength building exercises like push - ups and planks with dance - like movements.
Dr. Gregg Fonarow, a professor
of cardiology at the University
of California, Los Angeles, said prior
studies where lower doses
of omega - 3 fatty acids were given after heart attacks had yielded «
mixed results.»
A similar drug, Adderall, is composed
of mixed amphetamine salts and was not included in the
study results because it was first approved in 1996.
And 1 out
of 10 times, the mistakes in the
study resulted in pain and suffering, as in the tragic
mix - up that cost Eason her healthy breasts.
Soy milk formulas are often given to babies with milk allergy; but allergies to soy are almost as common as those to milk.18 Use
of soy formula to treat infant diarrhea has had
mixed results, some
studies showing improvement with soy formula while others show none at all.19 Soy formulas lack cholesterol which is absolutely essential for the development
of the brain and nervous system; they also lack lactose and galactose, which play an equally important role in the development
of the nervous system.
Use
of soy formula to treat infant diarrhea has had
mixed results, some
studies showing improvement with soy formula while others show none at all.
But clinical trials that have tested cranberry products have yielded
mixed results, possibly because
studies tested juices and supplements with varying amounts
of active ingredients.
Disappointments with outcomes - based
studies investigating α - tocopherol are, in large part, the
result of abstracting this single compound from the vitamin E family and ignoring the interplay among the eight isomers that constitute natural vitamin E. Best clinical outcomes will be achieved with vitamin E supplementation providing
mixed tocopherols and tocotrienols in ratios similar to those found in nature.
However,
studies provide
mixed results and whether butter truly increases the risk
of chronic disease is hotly debated.
Bone health, cardiovascular health, and cancer prevention are among the areas that have been closely
studied — with a variety
of mixed results.
(3) In small human performance
studies, the performance
results of high fat (ketogenic) diets are
mixed.
Some preliminary
studies have shown
mixed results in terms
of chia seeds promoting weight loss.
Based on the
mixed results of these animal
studies and a lack
of research in pregnant women at this time, it may be best to limit flax to occasional small doses during pregnancy.
However, the
results of clinical
studies investigating the memory enhancement benefits
of ginkgo are
mixed.