Sentences with phrase «mode of inheritance as»

It is difficult to control disorders with a polygenic mode of inheritance as the exact genes which cause such a disease and the non-genetic factors which will influence expression are unknown.

Not exact matches

In a commentary accompanying the report, Paul Soloway of Cornell University remarks: «A particularly intriguing possibility is that such RNAs regulate other non-genetic modes of inheritance, such as metabolic or behavioral imprinting.»

Little is known about the mode of inheritance; that is, whether they are simple as progressive retinal atrophy and sebaceous adenitis are in some breeds or are, like hip dysplasia, a complex association of many genes.

Dramatic, complete and immediate removal of carriers from a closed / highly related population such as Italian Greyhound's would definitely not be recommended if we were certain of an Autosomal Recessive mode of inheritance.

As there is no evidence to suggest a mode of inheritance for this problem, CERF considers it a «breeder option» to breed affected animals.

Epilepsy in beagles was thought to be homologous to Lafora's disease in man based on the similar findings from histopathological examination 23 and the mode of inheritance was described as autosomal recessive with a sex - linked «suppressor» 4, 5.

Genetic disorders without a known mode of inheritance should be managed in the same way as polygenic disorders.

As stated by Dr. Rubin, it has been assumed that the mode of inheritance is recessive (both parents are carriers), and affected animals are not to be considered to have normal eyes.

PHPV / PTVL is recognized as inherited in some breeds but no mode of inheritance has been identified in breeds thus far studied.

A recessive mode of inheritance has been suggested for congenital cataracts and microphthalmia in the Miniature Schnauzer [112] as well as cataracts in the Entlebucher mountain dog [113], the Bichon Frise [114] and the American Cocker spaniel [115].

Retinal dysplasia appears to be inherited as an autosomal trait, at least in those breeds where sufficient numbers of individuals have been studied to reliably estimate the mode of inheritance [82 — 84].

In contrast, an autosomal dominant mode of inheritance with a high degree of penetrance has been suggested for the pulverulent (dust - like) form of cataract observed in the Norwegian Buhund [116] and autosomal dominant with variable penetrance has been suggested for inherited posterior polar subcapsular cataracts in the Labrador and Golden retriever [117], although current anecdotal evidence indicates that in the Labrador cataracts could also be inherited as an autosomal recessive trait.

The mode of inheritance is as an «autosomal recessive.»

The mode of inheritance for this condition for many years now has been characterized as autosomal recessive meaning that affected dogs have inherited the mutant gene from both parents.