Sentences with phrase «model mice experience»

Typically, MS - model mice experience severe motor problems, eventually leading to paralysis, but when they were given the drug the mice behaved perfectly normally.

Not exact matches

The behavioral tests used here modeled one dimension of the disease — an inability to experience pleasure from normal activities — but not others, such as stress and anxiety, and probably tap into different brain mechanisms in mice than in humans, he says.

«Our MICE model uses whale numbers dating back from 1890 to now and then couples this with food availability and ocean physics to understand the changes to ocean conditions that whales are likely to experience,» Dr Plaganyi said.

«Despite the low infection levels of mouse cells with oHSV, we were able to cause a delay in tumor growth in one of the cancer models and even cure many of the mice in a second model,» said first author Jennifer Leddon, who conducted much of the laboratory work during a research experience in the Center for Childhood Cancer and Blood Diseases.

Studies in humans have shown that up to 60 % of individuals with ASD experience SWDs during sleep, despite no diagnosis of clinical epilepsy, suggesting accuracy of the mouse model.

Researchers from Massachusetts Eye and Ear / Harvard Medical School have identified inflammatory factors that cause optic neuropathy in the back of the eye following implantation of a keratoprosthesis (KPro)-- similar to what glaucoma patients experience, without the rise of pressure in the eye — and have shown that blocking one of those factors, tumor necrosis factor alpha (TNFa), successfully halts the development of optic nerve damage in a mouse model.

Laboratory mouse models are commonly used to study A-T; however, mice with A-T do not experience the more debilitating effects that humans do.

Prior experience in manipulation of anaerobic microbes, mouse infection models, analytical chemistry or bioinformatics are desirable (but not required).

His lab has extensive experience evaluating and modulating T cell responses to tumors and viruses, including introducing genes into T cells to impart specificity and modulate function, designing strategies to overcome tolerance and enhance in vivo activity, and developing mouse models that more accurately model human immune responses to candidate vaccines.

In addition to her expertise in tumor biology and a broad network of connections with leading scientists and clinicians in cancer research and clinical oncology, Dr. Almog has extensive hands - on experience with a variety of techniques ranging from the molecular level (DNA, RNA and proteins) to tissue, organ and mouse models in cancer biology, as well as extensive experience in project management and program coordination.

Dr. Burcham also has experience with laboratory animal pathology, specifically mouse models of neoplasia and autoimmune disease.