Sentences with phrase «model mice fed»

Abstract: We previously reported that neuroinflammation contributes to the amnesia of AβPPswe / PSEN1dE9 Alzheimer's disease model mice fed a high - fat diet to induce type - 2 diabetes (T2DM - AD mice), but the underlying mechanism for the memory decline remained unclear.

Not exact matches

In the new work, published June 10 in the journal Scientific Reports, Zhao, Reid and colleagues used a highly sensitive probe to measure electrical fields in the corneas of isolated eyes from three different lab mouse models with different types of diabetes: genetic, drug - induced and in mice fed a high - fat diet.

Intriguingly, in the new study, the brains of mice modeling autism that were fed the high - glycemic index diet had drastically less doublecortin, a protein indicator of newly developing neurons, compared to predisposed mice on the low - glycemic index diet.

The prevention of dilated cardiomyopathy in a mouse model by feeding a high - fat diet signals an advance in the understanding of the mechanisms involved in heart disease and has implications for the future development of treatments for this condition.

The researchers, therefore, decided to study whether oral F. prausnitzii treatment would decrease hepatic fat content in high - fat fed mice that serve as a model for fatty liver.

Liang thinks rats make better models of human feeding behaviors than mice because rats are bigger mammals and eat significantly more than mice, making it easier to measure their food intake.

In this study, NIH scientists used mouse models to show that anthrax toxin proteins work by specifically targeting the cells that line the inner walls of the blood vessels feeding the tumor.

We used a mouse model of continuous intragastric feeding of alcohol or an isocaloric diet.

In the first study, published in Hepatology, we used a mouse model of continuous intragastric feeding of alcohol with mice fed a non-alcoholic diet of similar caloric intake as controls.

Fenster will use the fellowship to support his work on improving the understanding and treatment of early life stress, and Ross will use her award to support research on determining whether certain neurons in the ventromedial prefrontal cortex can direct feeding decisions in a mouse model.

In rodents, ketogenic diets reduce reactive oxygen species in the brain34 and reduce central inflammation and reactive oxygen species in a model of multiple sclerosis.35 Two clinical papers have found that ketogenic diet feeding of 12 weeks to 6 months reduced signs of liver inflammation in obese patients with nonalcoholic fatty liver disease (in addition to improving various other physiological and biochemical variables).36, 37 Unfortunately, basic research into non-alcoholic fatty liver disease has been hampered by species differences between mice and humans in their hepatic reaction to ketogenic diets.38

Studies in animal models of NAFLD have shown that nicotinamide mononucleotide supplementation corrects biochemical and microscopic liver changes in mice fed a high - fat diet.65, 66

From a kitty playground to a napping pod modeled after a lunar spaceship (and equipped with built - in feeding bowls and astro - mice toys), they're intriguing for both cats and humans.