Sentences with phrase «model of allergic asthma»
Asano T, Kume H, Taki F, et al: Thalidomide attenuates airway hyperresponsiveness and eosinophilic inflammation in a murine model of allergic asthma.
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Here, we show that in germ - free (GF) mice, invariant natural killer T (iNKT) cells accumulate in the colonic lamina propria and lung, resulting in increased morbidity in models of IBD and allergic asthma as compared with that of specific pathogen - free mice.
Lead researchers Associate Professor Chrishan Samuel and Dr Simon Royce tested the efficacy of the MSCs on three key components of asthma in a preclinical model of chronic allergic airways disease: inflammation; airway remodeling (structural changes that occur in lungs as a result of prolonged inflammation); and airway hyperresponsiveness (the clinical symptom of asthma).
RIPK2 gene silencing in the airways decreased allergic airway inflammation in an ovalbumin - mediated mouse model of asthma (Jun et al., 2013).