Sentences with phrase «model of translational research»
«This is expected to be the first of many new innovative therapies made possible by the Wyss Institute's collaborative model of translational research that will enter human clinical trials,» said Wyss Founding Director Don Ingber, M.D., Ph.D., who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical School and Boston Children's Hospital, and a Professor of Bioengineering at Harvard SEAS.
https://www.sciencedaily.com/
The effort is the fruit of a new model of translational research being pursued at the Wyss Institute for Biologically Inspired Engineering at Harvard University that integrates the latest cancer research with bioinspired technology development.
Not exact matches
In 2015, Noebels and Dr. Isamu Aiba, a research fellow in neurology at Baylor, published a paper in Science Translational Medicine in which they described in a mouse model what would happen if spreading depolarization, the blackout of brain activity, occurred deep in the brainstem, which controls the heart beat and breathing.
His research efforts are divided between preclinical models, the development, performance, and monitoring of cancer immunotherapy trials and the training of the next generation of translational investigators.
The journal's home page explains that translational medicine «builds on basic research advances — studies of biological processes using cell cultures, for example, or animal models — and uses them to develop new therapies or medical procedures.»
«Modeling the process of translational science, it is clear that greater emphasis needs to be placed on expediting the growth of basic biomedical research to improve the efficiency, timelines, and cost of bringing new cures to market.»
«It's a dramatic increase in lifespan of animal models, as much as 25 percent,» said Leyuan Liu, PhD, assistant professor at the Texas A&M Institute of Biosciences and Technology's Center for Translational Cancer Research.
«This study shows how translational research using basic science techniques in animal models can elucidate the underlying basis of human emotions and reasons for mental disorders, thereby pointing the way for treatment development,» says Jeffrey Lieberman, MD, Lawrence C. Kolb Professor and Chair of Psychiatry at CUIMC.
We carry out translational research programmes to develop infectious disease vaccines, therapeutics and diagnostics using animal models of tuberculosis, influenza, HIV / AIDS, Clostridium difficile, meningococcal disease, chlamydia, burkholderia and anthrax, as well as emerging viral diseases such as Crimean Congo haemorrhagic fever.
Additionally, the Institute's recent alliance with the California Institute for Biomedical Research (Calibr) adds translational research to its capabilities, enabling a new bench - to - bedside model that will accelerate the translation of basic scientific discoveries into critically - needed new medicines for unmet medicaResearch (Calibr) adds translational research to its capabilities, enabling a new bench - to - bedside model that will accelerate the translation of basic scientific discoveries into critically - needed new medicines for unmet medicaresearch to its capabilities, enabling a new bench - to - bedside model that will accelerate the translation of basic scientific discoveries into critically - needed new medicines for unmet medical needs.
Models of interinstitutional partnerships between research - intensive universities and minority serving institutions (MSI) across the Clinical Translational Science Award (CTSA) Consortium.
These models are used for both basic and translational research, including studies to investigate the role of tumor initiating cells in tumor relapse, tumor metastasis and therapy resistance.
This research was supported by the NIH (R01 AR062368, R01 AR062920 to A.J.G and R01 DK055679, R01 DK059888, DK055679, DK059888, and DK089763 to A.N.), and J.R.S. is supported by the Intestinal Stem Cell Consortium (U01DK103141), a collaborative research project funded by the National Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Institute of Allergy and Infectious Diseases (NIAID), and by the NIAID Novel, Alternative Model Systems for Enteric Diseases (NAMSED) consortium (U19AI116482), PHS Grant UL1TR000454 from the Clinical and Translational Science Award Program, and a seed grant from the Regenerative Engineering and Medicine Research Center between Emory University, Georgia Tech and the University of research was supported by the NIH (R01 AR062368, R01 AR062920 to A.J.G and R01 DK055679, R01 DK059888, DK055679, DK059888, and DK089763 to A.N.), and J.R.S. is supported by the Intestinal Stem Cell Consortium (U01DK103141), a collaborative research project funded by the National Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Institute of Allergy and Infectious Diseases (NIAID), and by the NIAID Novel, Alternative Model Systems for Enteric Diseases (NAMSED) consortium (U19AI116482), PHS Grant UL1TR000454 from the Clinical and Translational Science Award Program, and a seed grant from the Regenerative Engineering and Medicine Research Center between Emory University, Georgia Tech and the University of research project funded by the National Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Institute of Allergy and Infectious Diseases (NIAID), and by the NIAID Novel, Alternative Model Systems for Enteric Diseases (NAMSED) consortium (U19AI116482), PHS Grant UL1TR000454 from the Clinical and Translational Science Award Program, and a seed grant from the Regenerative Engineering and Medicine Research Center between Emory University, Georgia Tech and the University of Research Center between Emory University, Georgia Tech and the University of Georgia.
The ITCMS program, in its 41st year, was established to provide postdoctoral fellows an interdisciplinary training experience, including basic and translational research opportunities with renowned investigators, and an extensive scope of workshops and training modules with an emphasis on cancer model systems.
Appropriate animal models and translational research to study sex differences are needed to get more insight into the pathophysiology and complex interplay of hormones, genes, lifestyle, and environment.
The Center for Predictive Medicine recognizes the challenges of translational research such as in designing and implementing high - throughput screens and assessing small molecules and potential vaccines for their efficacy in small animal models of disease.
The role of αCaMKII autophosphorylation in the establishment of alcohol addiction Alanna Easton, King's College, UK Novel age - dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research Karienn Montgomery, University of Florida, USA Microsatellite regions upstream of the vole Avpr1a gene contribute to both individual and species differences in receptor expression Zoe Donaldson, Columbia University, USA Per Genes and Addiction Stephanie Perreau - Lenz, Central Institute of Mental Health, Germany
Topics covered include embryonic stem cells, pluripotency, germline stem cells, tissue - specific stem cells, stem cell differentiation, epigenetics, stem cell genomics and systems biology, genome reprogramming, cancer stem cells, stem cell niches, stem - cell - based disease models, nuclear transfer technology, bioengineering, drug discovery, in vivo imaging of stem cells, therapeutic applications, regenerative medicine, clinical and translational insights, stem cell research policies, ethical issues, and technical or resource - based innovations.
Researchers at the National Institute of Neurological Disorders and Stroke and the National Institutes of Health recently designated SMA as a model for translational research funding, which uses basic scientific research to devise actual drugs and treatments.
Dr. Falk is also PI of an NIH, pharma, and philanthropic funded translational research laboratory group at CHOP that investigates the causes and global metabolic consequences of mitochondrial disease, as well as targeted therapies, in C. elegans, zebrafish, mouse, and human tissue models of genetic - based respiratory chain dysfunction, and directs multiple clinical treatment trials in mitochondrial disease patients.
The National Institute of Neurological Disease and Stroke recently designated spinal muscular atrophy as the model for its new approach to funding «translational research.»
She is the Principle Investigator of the I - SPY TRIAL program, a multi-site neoadjuvant clinical trial (which includes phase 2 and 3 trials) that has evolved into a model for translational research and innovation in clinical trial design.
The ITCMS postdoctoral training program at the UNC Lineberger Comprehensive Cancer Center provides an exceptional interdisciplinary training experience, including outstanding basic and translational research opportunities with renowned investigators, and an extensive scope of workshops and training modules with an emphasis on cancer model systems.
Oncology investigators in the NC State Center for Comparative Medicine and Translational Research, for example, focus on understanding the pathogenesis and treatment of cancer through studies involving, in part, spontaneous models of cancer provided by Terry Center oncology patients.
My lab is is a research unit of the Department of Surgery located on the veterinary hospital campus, primarily focused on translational research using complex nonhuman primate (NHP) disease models and screening rodent models.
Supporting high - value, contemporary, best practice care: enhanced funding for translational research; quality improvement measures across the health system; a longer term, more sustained model of MBS review.