Sentences with phrase «model organisms»

This finding represents one of the first examples of a genome - wide significant genetic factor to be identified for binge eating in model organisms or humans.

-- 90 percent of genes associated with disease are identical in the human and the mouse, supporting the use of mice as model organisms.

She is a strong advocate for basic research and the use of model organisms in biological research.

My group uses model organisms to understand the molecules that control the tempo of development.

This follow - up investigation also could use the tissue - sharing program, but researchers say they need a larger number of samples from model organisms that had longer exposure to space.

The research opens the possibility of a new model organism for human heart health and the distant prospect of incorporating such a gene into humans.

While many of these patterns were similar in human and mouse, the dominant genetic model organism for biomedical research, many genes showed different patterns in human.

It is found in nearly all countries and, as the laboratory mouse, serves as an important model organism in biology; it is also a popular pet.

As these different techniques become available, researchers could simultaneously apply them to different model organisms.

Similarly, decades of research in various model organisms, from mouse to yeast, are also stored in their own individual databases with different sets of standards.

The fruit fly is an ideal model organism for such a task, because of its sophisticated genetic tools to analyze neurons and manipulate neural circuits in the brain.

The sequencing of the human genome is gearing up all those efforts, and with each novel model organism for which the sequence has been determined, the power of comparative analysis increases.

Studies of the brains of model organisms do allow for investigations of how brain activity arises from groups of neurons and how different groups of neurons interact with each other.

We focus on several model organisms in the laboratory but are open to additional approaches by independent - minded and motivated individuals.

The stick insect is a popular model organism in biological research for gaining a better understanding of insect walking movements.

And this is where yeast, worms and flies can help: Although they may not look it, these so - called model organisms share a lot of genetic information with humans.

That helps us make decisions about what model organisms are worth investing biomedical research in.

The technology has thus far been applied to produce spectacular proof of principle recordings of model organism embryos which capture the developing specimen at cellular resolution throughout early development.

Now, the use of diverse model organisms to explore human disease is truly starting to gain the recognition it deserves as a scientific approach.

And it turns out that this yeast is the perfect model organism for this study.

Understand how lipid ordering affects membrane organization and protein dynamics and function using bacterial model organisms.

Basically, it's the place you can publish your obscure model organism's draft genome.

The same goes for the numerous model organisms commonly used in life science, rendering an enormous number of individual protein targets of interest to scientists.

These may cover the exchange of biomedical and genetic data, linking mouse model organism data with human clinical information, and the deposition of large volumes of data from one project to another.

He also believes the technique will work reasonably well for studying the structure and function of proteins in most other model organisms, including laboratory mice.

This failure makes it harder for the public to understand the value of model organism research, which in turn threatens its funding.

So he went in search of a new model organism.

The less - complex nervous system of the fruit fly makes them easier to study than people or even mice, another genetic model organism.

The water flea is a key species in aquatic ecosystems and an important model organism in biology and environmental genetics.

In the last few years, several studies have shown that gene therapy, especially if applied early, can stop or reverse some forms of congenital blindness in model organisms.

The most well - studied species on the planet are called model organisms, creatures chosen for intensive research because they are particularly suited to laboratory studies.

GSA member Janan Eppig, who is PI for the Mouse Genome Database, and Monte Westerfield, who runs the Zebrafish Model Organism Database, are concerned about this precedent.

In a 2012 paper in Neuron, based on meetings organized by the Oxnard, California - based Kavli Foundation, Yuste and colleagues laid out a plan to progress gradually from mapping the brain activity of simple model organisms such as the fruit fly to charting the brains of creatures that contain roughly 1 million neurons, such as the Etruscan shrew.

In 1997, when few genome sequences were available, Hieter helped create XREFdb, a public database that linked the functional annotations of genes studied in model organisms with the phenotypic annotations on the human and mouse genetic maps.

And much of that progress was fueled by work on model organisms like Drosophila.

Fruit flies serve as a good model organism for understanding the molecular mechanisms behind many human diseases — around 75 percent of disease - causing genes are found in the species in a similar form.

In experiments on the fruit fly model organism Drosophila melanogaster, Heidelberg University biologists gained new insight into how feeding behaviour is encoded and controlled.

Currently, Brainbow techniques are also being applied to study model organisms such as Drosophila and zebrafish.

«For years, fruit flies and worms have been great model organisms because of the ability to carry out rapid genetic screens,» says Elaine Fuchs, Rebecca C. Lancefield Professor.

«By means of basic research on model organisms, we are trying to understand human genome instability to identify elements, which, in the future, might be able to be explored as targets of new anti-tumour medicines,» explains the researcher responsible for the project and director of Cabimer, Andrés Aguilera.

Two years ago at the 2014 Avian Model Systems 8 conference, the only mention of CRISPR / Cas9 was in reference to its future use in passenger pigeon de-extinction — despite CRISPR / Cas9's rapidly spreading use in other model organisms at the time.

The resulting collaborations are crucial to advancing our knowledge of biology, including human health and disease; connecting model organism researchers and human biologists with one another speeds progress for both groups, facilitates mechanistic understanding of disease gene functions, and helps uncover novel disease mechanisms and candidate therapeutic targets.

Introducing new antibody chains is becoming practically routine in the field of genome editing; genetic engineering of antibodies for human health purposes has steadily advanced over the past few decades using many model organisms including rodents, cattle, and even chickens.

To address these questions we are using a two - model organism approach studying the metanephric kidney of mouse and the pronephric kidney of Xenopus laevis.

Transparent eggs and fry are «ideal for getting light in and getting light out,» notes Eric Edsinger, who develops model organisms at the Marine Biological Laboratory in Woods Hole, Mass..