Sentences with phrase «model systems where»

Thanks to genome sequencing and other methods there's been an explosion of emerging model systems where one can now reap the benefits of studying unique aspects of biology.

«I can now take virtually any organism and manipulate the genome and create model systems where I can track cells, manipulate genes,» says Gitlin.

«By modelling a system where females can mate multiply to enhance fertility, and males compete for fertilization of female eggs, researchers show that male choosiness readily evolves.

To achieve this they used a model system where an enzyme called p110 alpha was genetically modified in mice.

The multinational research group utilized a model system where human retinal pigment epithelial cells were infected with Zika virus strain they isolated earlier from fetal brain [T1].

Not exact matches

It is no coincidence that the school system in Finland, the darling of the international educational community for its superior test scores, is built on an experience - based model, where science and math are taught through doing, and labs take precedence over textbooks.

Instead of an auction model, where consumers post jobs and contractors bid on them, in the new system, contractors post their hourly rates, taking a step out of the booking process.

According to a fascinatingly nerdy deep dive into the subject in the New Yorker, the current mania for the word «hack» all started way back in the 1950s at MIT, where members of the model railroad club were already warning those «hacking on the electrical system turn the power off to avoid fuse blowing.»

«We've seen this before,» he added, «where we've had very smart, very talented people have a knee - jerk reaction to this because they're applying old mental models to a new system.»

The exciting opportunity for startups is to skate to where the puck is going — by thinking beyond exploitative legacy business models that amount to embarrassing blackboxes whose CEOs dare not publicly admit what the systems really do — and come up with new ways of operating and monetizing services that don't rely on selling the lie that people don't care about privacy.

The reason for this is that the nation's ideology had changed where it had once trumpeted the ideas of non-intervention and peace (except, of course, for the people of the South during their heroic attempt at independence) to those that glorified empire and war, largely based on the British model which, ironically, was the system that America seceded from in 1776.

The clean resolution to the attempted heist was possible due to a new, decentralized, governance model where those with stake in the system cast their decisive votes.

The sentiment seemed widespread on tech and media Twitter: there was a lack of specificity in terms of questions about privacy (this allowed Zuckerberg to turn nearly every question about the ownership of data to a discussion about user interface controls that limit where data is shown to other Facebook users), plenty of dodged questions (every time there was a question about the data Facebook generates about users beyond what they themselves enter into the system Zuckerberg needed to «check with his team»), and bad questions that presumed Facebook sells data, letting Zuckerberg run out the clock at least three times by explaining the basics of Facebook's business model (this is precisely why I have been so outspoken about the problem of perpetrating this falsehood: it lets Facebook off the hook).

«It means reversing this long time economic model, where the state will profit through the economic system at the expense of the consumers and household, and one of the things that the new leadership is intent on doing in order to create consumption is to empower consumers, so they spend more and stop empowering state organizations which are fuelling the overcapacity and the massive debt bubble».

The platform's core model, Reichman said, is predicated on a < br / > distributed system where a worldwide collective of content generators curate < br / > short news submissions, or «snips,» that are then read by others on the site.

This is where we come into the picture: our technology makes it possible to model these systems and the semiconductors that will be integrated in them, so that it will be possible to test the vehicle software on them before the hardware that runs it has been developed in the real world.»

The system of symbols wherein the revelation is conveyed is articulated beyond the point where models for a vision of the world and models for changing the world diverge.

Operators are facing four big areas of challenge that Technomic sees as transformative, bound to drive changes in how operators approach business: 1) coping with supply chain challenges, including driver shortages; 2) meeting consumer demand for «food with integrity»; 3) dealing with «regulation nation» where industry - disrupting changes may include a higher minimum wage; and 4) incorporating innovations into operations, including new delivery models, variable pricing, self - ordering systems, and robotics.

The model railroaders are allotted a 20 - by - 30 room in the clubhouse where they have set up and are forever playing with toy railroad systems.

This is an incredibly difficult question to answer for a variety of reasons, most importantly because over the years our once vaunted «beautiful» style of play has become a shadow of it's former self, only to be replaced by a less than stellar «plug and play» mentality where players play out of position and adjustments / substitutions are rarely forthcoming before the 75th minute... if you look at our current players, very few would make sense in the traditional Wengerian system... at present, we don't have the personnel to move the ball quickly from deep - lying position, efficient one touch midfielders that can make the necessary through balls or the disciplined and pacey forwards to stretch defences into wide positions, without the aid of the backs coming up into the final 3rd, so that we can attack the defensive lanes in the same clinical fashion we did years ago... on this current squad, we have only 1 central defender on staf, Mustafi, who seems to have any prowess in the offensive zone or who can even pass two zones through so that we can advance play quickly out of our own end (I have seen some inklings that suggest Holding might have some offensive qualities but too early to tell)... unfortunately Mustafi has a tendency to get himself in trouble when he gets overly aggressive on the ball... from our backs out wide, we've seen pace from the likes of Bellerin and Gibbs and the spirited albeit offensively stunted play of Monreal, but none of these players possess the skill - set required in the offensive zone for the new Wenger scheme which requires deft touches, timely runs to the baseline and consistent crossing, especially when Giroud was playing and his ratio of scored goals per clear chances was relatively low (better last year though)... obviously I like Bellerin's future prospects, as you can't teach pace, but I do worry that he regressed last season, which was obvious to Wenger because there was no way he would have used Ox as the right side wing - back so often knowing that Barcelona could come calling in the off - season, if he thought otherwise... as for our midfielders, not a single one, minus the more confident Xhaka I watched played for the Swiss national team a couple years ago, who truly makes sense under the traditional Wenger model... Ramsey holds onto the ball too long, gives the ball away cheaply far too often and abandons his defensive responsibilities on a regular basis (doesn't score enough recently to justify): that being said, I've always thought he does possess a little something special, unfortunately he thinks so too... Xhaka is a little too slow to ever boss the midfield and he tends to telegraph his one true strength, his long ball play: although I must admit he did get a bit better during some points in the latter part of last season... it always made me wonder why whenever he played with Coq Wenger always seemed to play Francis in a more advanced role on the pitch... as for Coq, he is way too reckless at the wrong times and has exhibited little offensive prowess yet finds himself in and around the box far too often... let's face it Wenger was ready to throw him in the trash heap when injuries forced him to use Francis and then he had the nerve to act like this was all part of a bigger Wenger constructed plan... he like Ramsey, Xhaka and Elneny don't offer the skills necessary to satisfy the quick transitory nature of our old offensive scheme or the stout defensive mindset needed to protect the defensive zone so that our offensive players can remain aggressive in the final third... on the front end, we have Ozil, a player of immense skill but stunted by his physical demeanor that tends to offend, the fact that he's been played out of position far too many times since arriving and that the players in front of him, minus Sanchez, make little to no sense considering what he has to offer (especially Giroud); just think about the quick counter-attack offence in Real or the space and protection he receives in the German National team's midfield, where teams couldn't afford to focus too heavily on one individual... this player was a passing «specialist» long before he arrived in North London, so only an arrogant or ignorant individual would try to reinvent the wheel and / or not surround such a talent with the necessary components... in regards to Ox, Walcott and Welbeck, although they all possess serious talents I see them in large part as headless chickens who are on the injury table too much, lack the necessary first - touch and / or lack the finishing flair to warrant their inclusion in a regular starting eleven; I would say that, of the 3, Ox showed the most upside once we went to a back 3, but even he became a bit too consumed by his pending contract talks before the season ended and that concerned me a bit... if I had to choose one of those 3 players to stay on it would be Ox due to his potential as a plausible alternative to Bellerin in that wing - back position should we continue to use that formation... in Sanchez, we get one of the most committed skill players we've seen on this squad for some years but that could all change soon, if it hasn't already of course... strangely enough, even he doesn't make sense given the constructs of the original Wenger offensive model because he holds onto the ball too long and he will give the ball up a little too often in the offensive zone... a fact that is largely forgotten due to his infectious energy and the fact that the numbers he has achieved seem to justify the means... finally, and in many ways most crucially, Giroud, there is nothing about this team or the offensive system that Wenger has traditionally employed that would even suggest such a player would make sense as a starter... too slow, too inefficient and way too easily dispossessed... once again, I think he has some special skills and, at times, has showed some world - class qualities but he's lack of mobility is an albatross around the necks of our offence... so when you ask who would be our best starting 11, I don't have a clue because of the 5 or 6 players that truly deserve a place in this side, 1 just arrived, 3 aren't under contract beyond 2018 and the other was just sold to Juve... man, this is theraputic because following this team is like an addiction to heroin without the benefits

Unlike older so - called Universal remotes where you had to point it at the television and press and press until it searched for the code, the Harmony systems allows you to simply enter in the manufacturer name and model name / number and find it.

And I think, again, I see the model practice as one that gives the woman the greatest number of choices, a model practice where you actually have the time and the capacity on the patient's part to understand the risks and benefits of each of the subsequent choices to have a relatively smooth system, which can transfer from one model of birth to another without extensive delays and then — and so I think giving the mom the greatest number of choices and having midwives and physicians speaking to each other at the time of either the initial patient's choice for method of delivery or at the beginning of the labor process.

Not all areas of the world have health systems where midwives are able to provide midwife - led continuity models of care, and health system financing is a potential barrier to implementation.

Now that the education of midwives has moved mainly into the university clinical model, we are on the verge of having a monoculture of birth where there is only one way for birth to unfold in the system.

Not all areas of the world have health systems where midwives are able to provide midwife - led continuity models of care (De Vries 2001) and health system financing is a potential barrier to implementation.

A close analysis of these indicators makes clear that dignity and a dignity - based model of governance do not necessarily overlap with liberal democratic values and systems of government, where exclusion and injustice can run rampant.

It is also why developments in the business of digital journalism matters for democracy, especially in countries like the U.S., where private sector media provide by far the largest share of news coverage of public affairs, because of the low levels of funding for public media — as commercial media organizations in many countries continue to lose revenue and lay off reporters because their legacy platforms (like print) grow less popular by the day, the future of the private media sector, an important part of our democratic systems, depends in part on its ability to find new business models and reinvent itself for a new century and new media world, online and elsewhere.

It's considerably higher than the 15 percent cap proposed by Gov. Andrew Cuomo — which he modeled after the U.S. Congress — but it is still a major shift from the current system, where legislators are considered part - time officials and allowed unlimited earnings in their side jobs.

The model of hospital administration in this publication actually has lots of semblance with contemporary models in the US, UK, Republic of Ireland, Australia and Canada where there is a board of directors / governors with a Chairman (does not have to be a Medical Doctor), a CEO / President / Hospital administrator (does not have to be a Medical Doctor) and a CMD / MD / CMO / Executive director medical services etc (Is ALWAYS a Medical Doctor — different names but similar portfolio — In Nigeria we always look up to these countries for direction with respect to global best practices so I do not understand what the commentator code - named afam6nr means by «Obviously, this writer has not attended any Business School Training and has no knowledge of Business Administration» — My advice to afam6nr is to do a little study of the different heath system of the world (specifically regarding corporate governance, organisation and administration of tertiary hospitals) and after this little research come back and comment on his findings!

«The new system is being modeled after the current development in the oil and gas sector where your carried interest is converted to a share of production so once the company produces, you receive your share of the products, sell them and use the proceeds to undertake developmental projects,» he explained.

In his budget proposal, the governor again included ethics and campaign fund - raising changes, including putting in place a system of public financing for state political campaigns modeled after the one used in New York City, where small donations are matched with public funds.

Professor Brilliantov added: «The rather general mathematical model elaborated in the study with the focus on Saturn's rings may be successfully applied to other systems, where particles merge, colliding with slow velocities and break into small pieces colliding with large impact speeds.

At this stage, researchers are developing mathematical models that could be written into the software needed to operate such a tracking system and are learning where to place sensors within a cabin to accurately trace hazardous airborne materials back to their source.

Or perhaps, he says, formation models need to be adjusted to make it easier for larger building blocks to grow in the outer solar system where comets form and where ice and organic molecules could assist in the sticking.

These observations and others have convinced the researchers that their CRISPR / Cas9 and hPSC system produces a stable, biologically accurate human model for a common genetic disease where new understanding and new therapies are desperately needed.

The system models where the water will go and produces updates every few minutes — a key advantage given that some areas can flood very quickly.

Here they used the UK - developed EPOCH «particle - in - cell» code, where particles are modeled as «chunks» that describe the bigger reality of the dynamics of the plasma system.

Unlike the Solar System where most of the gravitational pull comes from the Sun and is simple to model, it is much harder to describe the gravitational field near the centre of the Galaxy, where millions of stars, vast clouds of dust, and even dark matter swirl about.

The team has developed a three - layer model that illuminates the relationship between band members and the audience as a system, where emotions, expressivity and generation of sound give shape to improvisation.

The binary interaction model where a companion star is present is gaining traction because astronomers realize that at least 70 percent of massive stars are members of double - star systems.

They modelled relationships between environmental factors in the forest and where possums occurred to assign habitat suitability values, expressed as a percentage of the optimal habitat for the species, to both the current reserve system and possible expanded systems.

Based on information from satellites and other remote sensing systems, and reports on his movements since his last known location, the students created a probabilistic model of where he was likely to be.

The work relies on a model system called a Kondo chain, where flowing electrons interact with local magnetic moments within a material.

Other researchers point to the model of Finland, where educational theories, research methodologies and practice are all important parts of teacher education, according to Pasi Sahlberg, who in 2011 wrote Finnish Lessons, an account of how the country rebuilt its education system and rose to the top of international math and literacy rankings.

«Modelling has been used to help develop forecasting systems to predict flood risk around the shallower southern regions of the North Sea, where the coastal margin is low - lying and population density is high.

«With this novel animal model, we showed how it enhances fear rather than reducing it and where the molecular changes are occurring in our central nervous system.»

Dr Chen said: «Our model and its results can be used to understand realistic systems like pneumonia, where bacterium like Streptococcus pneumoniae interacts with viral respiratory infections like flu, and one pathogen increases the susceptibility towards the other up to 100-fold.

«Traditionally,» he explained, «if you want to train an automatic speech recognition system to detect a word like «Siri,» you need to have a training data set for which you know where in time this word appears... In my model, you only need to know how often the word appeared, but not when.

Jay Dunlap, PhDis co-PI on a U01 grant from the NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING entitled, «Multiscale modeling of circadian rhythms that seeks to mathematically model to Neurospora circadian system and its output, and to predict instances where metabolic output feeds back to impact the circadian clock.»

Confirming previous modelling of the Alpha Centauri system, the RECONS astronomers found that Alpha Centauri A and B orbit in such a way that when the light and heat of the two stars was combined, neither star in the innermost AB system significantly changed the size of their respective habitable zones, regardless of where each was currently located in its orbit.