Sentences with phrase «model validation studies»

Comparisons of models with data are, for example, referred to as model validation studies rather than model tests.

The analysis provides an estimate for the feedback terms that could be used for model validation studies.

Not exact matches

The researchers therefore acknowledge that «the models developed during this study require further validation using field collections.»

Diamond is also quick to point out that while the current study shows that COXEN could have been used to predict the most useful drug in many of these cases of advanced ovarian cancer, the actual use of the model will be possible only after validation with a prospective clinical trial.

«This is the first biological validation of a computational model developed in the early 1980s that suggested that two such forces would be necessary to guide axons as they establish the connections that relay spatial information from one part of the nervous system to another,» said study author Yimin Zou, PhD, assistant professor of neurobiology at the University of Chicago.

The ICS is a large - scale facility open to the community that ensures the generation of mouse models à la carte, the validation of genetic models, the expansion and preservation and distribution of models with the housing department, and offers in its phenotyping department a series of standardized functional analysis of mouse models that can be performed in a comprehensive pipeline or on demand, as well as for more specialized studies, that cover the major functions and key physiological systems.

The phenotyping platforms of PHENOMIN - ICS area, adapted to study genetically modified mouse models, can also be used for preclinical studies, including the validation of therapeutic targets, as well as pharmaceutical and toxicological studies in mice.

The role of new genetic pathways in cancer biochemistry (the genome mutation profiles), the identification of the key targets and their validation, as well as utilization of new knock - out or knock - in animal models for such studies are among topics that will be discussed.

This section invites manuscripts describing (a) Linkage, association, substitution or positional mapping and epigenetic studies in any species; (b) Validation studies of candidate genes using genetically - engineered mutant model organisms; (c) Studies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence varstudies in any species; (b) Validation studies of candidate genes using genetically - engineered mutant model organisms; (c) Studies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence varstudies of candidate genes using genetically - engineered mutant model organisms; (c) Studies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence varStudies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence varStudies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence variation.

Godwin's findings are a validation of the MDI Biological Laboratory's unique research approach, which is focused on studying regeneration in a diverse range of animal models with the goal of gaining insight into how to trigger dormant genetic pathways for regeneration in humans.

Researchers studying Mendelian and other genetic disorders in mice have new techniques and technologies to create new mouse models; paired with whole - exome sequencing, they have increased the rate of mutation discovery and validation tenfold.

«New Jersey had a rigorous process for vetting teacher evaluation models requiring a strong research - base and validation studies,» said Michael Toth, CEO, Learning Sciences International.

The validation studies include the linkage between teachers» use of classroom strategies and behaviors with gains in student learning contained within the model.

«One of the largest validation studies ever conducted on [the] observation framework shows that the Marzano model's research - based structure is correlated with state VAMs.»

One of the largest validation studies ever conducted on an observation framework shows that the Marzano model's research - based structure is correlated with state VAMs.

The upgraded Marzano Focused Teacher Evaluation Model streamlines current research and validation studies — zeroing in on 23 essential teacher competencies for improved clarity, efficiency, and effectiveness.

Model studies involve a process called «validation», the essence of which is testing how well the model (s) reproduce known climatic featModel studies involve a process called «validation», the essence of which is testing how well the model (s) reproduce known climatic featmodel (s) reproduce known climatic features.

More accurate and reliable precipitation data would be invaluable, not only for the study of climate trends and variability, but also as inputs to hydrological and ecological models and for model validation, characterization of extreme events, and flood and drought forecasting.

Therefore, this study casts considerable doubt on all current global warming models, which rely on this data as validation.»

Her main research interest is the quantification of uncertainty and validation of climate models, in particular with respect to extreme events, in order to undertake attribution studies of extreme weather events to external climate drivers.

Read the full study, including the section on Validation Against Modern CO2 Measurements and Ice Cores, Models / Methods and Model Boundaries and Sensitivity.

Validation of the GISS GCM: A Study of Ocean and Climate Modeling.

So in order to predict AGW accurately, the models need to be validated, and so far, with the exception of climateprediction.net, most validation studies I have read have failed to take into account the sensistivity of the models to parameter tuning.

FACES IV and the Circumplex Model: Validation Study.

First, we reported poor model fit for the alternative 3 - factor configuration; alternative validation studies observed adequate fit for both configurations using school - aged4 and preschool - aged16 populations.