Sentences with phrase «modeling study demonstrated»

In fact, as another recent modeling study demonstrated, planets in tight orbits around red dwarf stars might be getting lashed by an insane number of high - energy solar flares, stripping their atmospheres faster than they can be replenished.

However, Svensmark and colleagues, not wanting to wait for the credible quantitative results to come in, instead short circuited all of that tedious follow - up work, scaling up to realistic conditions, theoretical and modelling studies demonstrating that their effect was indeed viable, and simply declared in their press materials that the team had «discovered that cosmic rays play a big part in the everyday weather» and «brings to a climax a scientific quest that has lasted two centuries».

Not exact matches

To even question it will get you into trouble in a lot of circles... Martyn Shenstone and others have written exceptional studies demonstrating the dishonesty of this model... add this to the fact that this all happens where the richest 5 % of the planet are (which you are as well) and it is really out of whack...

Although many studies demonstrated the benefits of the best compression socks and the best compression shirts, but these studies all used different models, so their results are not conclusive.

The peer counseling model was based on published studies that demonstrate that, among peer counseling programs for low - income mothers of term infants, in - depth, in - person peer contacts are most effective.13, 15 Emphasis was thus placed on face - to - face contact, with meetings lasting at least 30 minutes.

Individual and group care models warrant additional study with a goal of demonstrating differences in outcomes and identifying populations that benefit most from specific care models.

This is demonstrated in the studies reviewed in the special issue, which use computational models to examine brain processes, such as learning, emotion, dopamine signaling and information processing, and how processes interact in deficits underlying psychiatric disease.

Engineered human immune cells can vanquish a deadly pediatric brain tumor in a mouse model, a study from the Stanford University School of Medicine has demonstrated.

This finding is important because it demonstrates the potential for broad applications of such models to study brain function, even for people with visual deficits.

The brochures contain information about toxicology, pharmacology, and animal safety studies used to determine the potential risk a particular therapy may pose to humans, but they also include efficacy studies done in animal models to demonstrate a therapy's potential benefit.

Researchers modeled kidney development and injury in kidney organoids (shown here), demonstrating that the organoid culture system can be used to study mechanisms of human kidney development and toxicity.

However, this new study could not demonstrate an association between muscle strength and cognitive function when using a model based on mere handgrip strength and age.

«This study, carried out using laboratory rats modeling stroke, demonstrated that ischemic stroke — in both its subacute and chronic stages — damages the BSCB in a variety of ways, creating a toxic environment in the spinal cord that can lead to further disability and exacerbate disease pathology,» said study lead author Dr. Svitlana Garbuzova - Davis, associate professor in USF's Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair.

The study demonstrates that a combination of modern reconstruction techniques and models can provide new insights into seasonal processes.

In this latest study, researchers were able to demonstrate the ability of the nanosensor to illuminate tumor tissue in multiple mouse models.

Interestingly, when compared to human cellular models, mouse models of PD did not demonstrate the same toxic cascade, according to the study.

The Oncotarget study demonstrated that Brenner's antibody worked in animal models of tumors that made cadherin - 11.

A new study in Geophysical Research Letters uses historical climate model simulations to demonstrate that there has been an Arctic - wide decrease in sea level pressure since the 1800's.

«The next stage would be to repeat the study in primates, a more suitable animal model where HIV infection induces disease, in order to further demonstrate elimination of HIV - 1 DNA in latently infected T cells and other sanctuary sites for HIV - 1, including brain cells,» Dr. Khalili said.

This is the first study to demonstrate an epigenetic model of nitric oxide signaling that has the potential to «change our fundamental understanding of both nitric oxide biology and epigenetic regulation,» Thomas said.

This dosing also exceeded the predicted human efficacious dose for AVI - 7288 estimated by three different models based upon the nonhuman primate studies that demonstrated up to 100 percent animal survival, including a delayed time - to - treat setting.

The study, called «Molecular Determinants of Drug - Specific Sensitivity for Epidermal Growth Factor Receptor (EGFR) Exon 19 and 20 Mutants in Non-Small Cell Lung Cancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patients.

«This study takes advantage of more than 25 years of observations and detailed model hindcasts to comprehensively demonstrate that these early predictions were right.»

Previous studies modeling outcomes have demonstrated that DBT can be cost effective.

«In our study, we were able to demonstrate in mouse models that Fas is activated within the scope of obesity and can therefore lead to the development of liver steatosis,» says Prof. Dr. med.

«To demonstrate this, our results will need to be replicated in clinical studies also designed to test the differential susceptibility model, this time not only assessing the impact of more or less coercive parenting methods, but also the impact of intervention programs targeting parenting practices.»

In the absence of such trials, mathematical models can help assess the effectiveness of different HIV intervention combinations, as demonstrated in a new study by Elisa Long and Robert Stavert from Yale University in the US.

The study, recently published in Nature Climate Change, is the first of its kind to clearly demonstrate the importance of modeling climate change, prey availability and their interactions in the development of management plans.

«This study for the first time shows increased expression of IL - 33 in AMD and further demonstrates a role for glia - derived IL - 33 in the accumulation of myeloid cells in the outer retina, loss of photoreceptors, and functional impairment of the retina in preclinical models of retina stress,» the authors note.

In a study recently published in the journal Experimental Haematology, the group demonstrate that is wide variation in BCR - ABL expression levels in the cell model and the stickier cells have a higher level of BCR - ABL expression.

«This is the first study to demonstrate that functional muscle cells can be created in a laboratory and restore dystrophin in animal models of Duchenne using the human development process as a guide.»

We've known that they couldn't all be perfectly round, but this study demonstrates you can use these derived values and improve predictions for more accurate models by accounting for differences in properties at different sizes and types of particulate matter.»

To demonstrate the device's capabilities, the researchers for the first time rotated C. elegans, a model organism about a millimeter in length that is frequently used in biological studies.

Druitt believes a pilot study using real data will demonstrate the validity of their model within the next 12 months.

This study provides one of the first animal models to demonstrate the long - term cognitive deficits resulting from a chemotherapeutic treatment used in treating humans for breast cancer.

«In this study we have demonstrated how novel concepts initially used to create a successful model of collaborative care for dementia were successfully applied to create the CCRC providing innovative collaborative care for ICU survivors,» she said.

The work demonstrated the process by which synapses are strengthened and weakened, making it possible to study and model how the brain learns.

Our current study aimed to provide proof - of - concept for this phenomenon in diabetes, and for that reason, we used the models and methodologies traditionally used in the prion field to demonstrate the transmission process.

During this BSA Distinguished Lecture, climate scientist Gavin Schmidt of the NASA Goddard Institute for Space Studies discusses climate models; assesses their strengths, limitations, and credibility; and demonstrates that they are, indeed, good for something.

Validating this original concept, we previously demonstrated that PGD - derived hES cells and their derivatives, which express the causal mutation implicated in the Myotonic Dystrophy type 1 (DM1), offer pertinent disease - cell models, applicable for a wide systemic mechanistic analysis ranging from functional studies at the cellular level to a large - scale drug screening.

Fallon said that in addition to the value of the findings themselves, the study demonstrates advances in creating animal models that can be used more successfully in mimicking the disease in ALS research, which is a key element in driving new research and possible therapies.

In parallel to these functional pathological studies, we also demonstrated the pertinence of this new disease - specific cell model to identify new therapeutic strategies.

Current in vitro hematopoiesis models fail to demonstrate the cellular diversity and complex functions of living bone marrow; hence, most translational studies relevant to the hematologic system are conducted in live animals.

Both empirical studies and model projections demonstrate that snowpack in the Northern Rockies and inland Pacific Northwest is more vulnerable to warming than some other regions in the West.

Validating this concept, we previously demonstrated that human pluripotent stem cells and derivatives which, express the causal mutation implicated in the Myotonic Dystrophy type 1 (DM1), offer pertinent disease - cell models, applicable for a wide systemic analysis ranging from mechanistic studies to therapeutic screening.

Collectively, the NHP studies convincingly demonstrate that the macaque model most closely resembles human borreliosis and provides the best experimental model to examine post-treatment persistence and associated disease.

In this study, we demonstrate that VPA treatment ameliorated GVHD in a mouse BMT model by downregulating Th1 and Th17 cells and reducing inflammatory cytokine levels via inhibition of the phosphorylation level of Akt in CD4 + T cells.

Overall, this study demonstrates that the climate simulated by a numerical climate model can be sensitive to how the snow albedo is treated.

This proof - of - concept study used preclinical models to demonstrate that the device was effective in reducing the cancerous tumour in the living brain.

This study is the first to investigate the phenotypic effects of the HAT activator CTPB, and to demonstrate that p300 / CBP HAT activation has neurotrophic effects in a cellular model of PD.