Hennebold is attempting to create these «knockout»
models for human diseases like hereditary blindness and deafness, among other disorders.
Not exact matches
«Finches offer researchers a new tool with which to study Huntington's
disease:
Like humans, songbirds learn their vocalizations, suggesting they could be useful as
models for certain disorders.»
Like humans, songbirds such as zebra finches (above) can learn vocalizations, and this similarity suggests they could serve as
models for research on Huntington's
disease and other neurodegenerative disorders that affect speech and vocalization.
«
For example, there is a huge amount of interest and excitement globally in growing cerebral organoids» — miniature brain -
like organs that can be studied in laboratory experiments — «from stem cells to
model human brain development and
disease mechanisms.
«Large animal
models of
human disease,
like cats, are really helpful
for determining what's going to happen in a child when you're treating them,» Vite said.
Colorado State University biologists say this sporadic ebb and flow of prairie dog plague is an ideal
model for the study of rare infectious zoonotic
disease —
disease that can jump from wildlife to
humans —
like MERS (Middle East Respiratory Syndrome) and Ebola.
It now looks
like many of these traits could be controlled by the combination of genes between different strains, thus producing mice that are better
models for human disease.»
for example, no HD mouse
model shows signs of «chorea», the dance -
like movements that are a common feature of the
human disease.
For such study, we have used the McGill - R - Thy1 - APP transgenic rat, which is unique compared to other rodent
models in that the AD -
like phenotype has been achieved with a single genomic insertion of a mutated
human APP transgene; minimizing off - target genetic corruption and therefore being closer to the
human disease [32].
Our in vitro study provides a baseline
for defining healthy and
disease -
like states and highlights the power of moving beyond single and dual species applications to capture key players and their orchestrated metabolic activities within a complex
human oral microbiome
model.
Cats and dogs that develop
diseases like cancer naturally are often better
models for human disease than lab rodents are, which is why more and more drug...