Sentences with phrase «models of actin»
Not exact matches
By using fruit fly as a model system, Minna Poukkula working at the Institute of Biotechnology, University of Helsinki, has found out how actin - rich protrusions contribute to cell migration in animal tissues.
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Dendritic Spine Density, Morphology, and Fibrillar Actin Content Surrounding Amyloid -[beta] Plaques in a Mouse Model of Amyloid -[beta] Deposition.
Senior author of the study Xuetong «Snow» Shen, Ph.D., associate professor in The University of Texas MD Anderson Cancer Center Department of Molecular Carcinogenesis, developed a unique model system to nail down actin's function in the nucleus: the actin - containing INO80 chromatin remodeling complex in yeast cells.
A breakthrough in understanding the mechanism of lamellipodial protrusion came from development of an in vitro model system, namely the rocketing movement of microbes and activated beads driven by actin comet tails (Cameron et al., 1999, 2000; Loisel et al., 1999; Theriot et al., 1994).
«George was one of the first biophysicists who married experiments and theory by developing computational models of a bewildering variety of molecular machines — kinesin motor, flagellar rotary motor, RNA polymerase and protein translocation motors, «one - shot» actin polymerization motor and «slime - gun» motor of bacterial gliding,» Magilner said.
On the basis of analysis of this system, we proposed a model for filopodial formation in which actin filaments of a preexisting dendritic network are elongated by inhibition of capping and subsequently cross-linked into bundles by fascin.
In this review, we will provide a detailed description of the organization and dynamics of F - actin and ABPs in dendritic spines and will discuss the current models explaining how the actin cytoskeleton sustains both structural and functional synaptic plasticity.