The company provides porcine
models of particular diseases, models that are used to develop gene - based treatments and drugs.
Not exact matches
«Use
of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable
of turning into other specific cell types relevant for studying a
particular disease — «makes it possible to
model dementias that affect people later in life,» says senior study author Catherine Verfaillie
of KU Leuven.
To narrow down the number
of chemical compounds that could be potential drug candidates, scientists utilize computer
models that can predict how a
particular chemical compound might interact with a biological target
of interest — for example, a key protein that might be involved with a
disease process.
A nomogram is a graphic depiction
of models that can be utilized to estimate the numeric probability
of death,
disease progression, or other events for a
particular patient.
In
particular, a transgenic mouse
model of early Alzheimer's
disease shows that the more focally targeted an intervention is, the more specific
of an effect can be elicited.
This workshop provides a week
of intensive training sessions in pathology and histopathology as well as didactic sessions in which
particular disease areas and
models will be discussed.
This has resulted in a dearth
of experimentally - validated
disease models for non-coding variants in
particular, despite their central importance in complex trait genetics.