Not exact matches
One of the biggest
studies done recently on nutrition, from the Women's Health Initiative Dietary
Modification Trial, showed no real benefits from a low - fat diet.
Screening, random assignment, and follow - up of the
study participants in the Swedish dietary and exercise behavior -
modification intervention
trial in lactating overweight and obese women.
Ward et al. highlight results from molecular and preclinical
studies, discuss clinical
trial results to date, describe ongoing investigations, and assess novel approaches for the enhancement of MSC based cardiac regeneration, such as genetic
modification.
27
Studies cited by the 2010 DGAC Report demonstrate varied metabolic responses to lowered dietary saturated fat, with certain subpopulations exhibiting adverse rather than improved health outcomes.3 Two recent comprehensive meta - analyses indicate that saturated fat is not linked to heart disease.28, 29 In fact, in a definitive review of forty - eight clinical
trials, with over sixty - five thousand participants, the reduction or
modification of dietary fat had no effect on mortality, cardiovascular mortality, heart attacks, stroke, cancer, or diabetes.30 Yet, avoiding saturated fat remains a cornerstone of national dietary guidance.
For example, more attention is being paid to the need for pilot and consultation work in the development phase of RCTs, 23 the importance of a more theory based approach to evaluation, 24 and the
modification of intervention effects by context in community intervention
trials.25 Statistical methods to integrate process and outcome data, such as those developed in the RIPPLE
study, are a move forward.