Sentences with phrase «modifications in a single gene»
Not exact matches
Because of these limitations, the AAV approach is best suited for tissue culture based approaches that require modification of only a single allele of a gene, such as the introduction of heterozygous endogenous epitope tags, or the introduction of dominant mutations of a gene into the endogenous allele in cultured cells.
http://blog.addgene.org/
«Although the whole proteome representation is simplified by adapting a gene centric point of view and disregarding post translational modifications, it still offers the first possibility of a proteome wide view of the autoantibody reactivity in healthy individuals and persons with autoimmune disorders, in one single experiment.»