On one end of the cascade is the so - called Unfolded Protein Response (UPR), and at the other end are numerous proteins with
modified glucose molecules attached to them.
The HBP is responsible for producing
modified glucose molecules that couple to numerous proteins, leading to beneficial changes in their function, stability, and location within the cell.
Not exact matches
He and his colleagues found a way to disable this system using a
modified version of
glucose that mimics the
molecules found on the surface of a fungus that attacks termites.
«Our work describes the structure and function of an important enzyme called Rumi, which adds a
glucose molecule to several signaling proteins to
modify their activities,» said the study's lead author, Huilin Li, a biologist at the U.S. Department of Energy's Brookhaven National Laboratory and Stony Brook University.
Prior to the current study, the scientists already knew that Rumi
modifies Notch by adding
glucose molecules to the protein.
From a chemistry point of view, glucosinolates are sugar - based
molecules that contain a
modified form of sugar (
glucose) together with sulfur and nitrogen.