According to the researchers these findings identify a uniquely
modified human protein that is required for Ebola virus to grow in cells.
A newly identified requirement of
a modified human protein in ebolavirus (EBOV) replication, may unlock the door for new approaches to treating Ebola.
Not exact matches
Actually, formula ingredients are made by
modifying cow's milk - based
protein and adding a milk sugar (lactose), fats, vitamins, and minerals to mimic the components of
human milk.
The U.S. Department of Agriculture has given a provisional go - ahead for genetically
modified rice containing
human genes to be grown in Kansas, despite concerns that the
proteins from the pharma rice could find their way into the food chain.
Soy
protein is significantly different in composition from cow milk
protein, but both are
modified to more closely resemble the amino acid content of
human milk (
human milk
protein is actually 40 % casein and 60 % whey).
The vast majority of babies fed a
human milk substitute are given
modified cow milk or soy
protein - based formula.
The drug - like compounds can be
modified and developed into medicines that target a
protein in the
human body that is responsible for chemotherapy resistance in cancers, said biochemist Pia D. Vogel, lead author on the scientific paper reporting the discovery.
Bacteria can be genetically
modified to produce various
proteins and other substances
humans need, so 3 - D printed bacterial materials may have many other medical uses, too.
Specifically, rodents genetically
modified to express
human amyloid precursor
protein (hAPP), which can lead to the debilitating plaques that form in the brains of Alzheimer's patients, seem to struggle to find the hidden platform relative to their healthy peers.
Since the February breakthrough, PPL Therapeutics of Edinburgh, which collaborates with the Roslin Institute, has produced five lambs from fetal cells that were genetically
modified to carry marker genes and genes for
human proteins.
Bancel showed Pangalos and his team two studies in which an injection of
modified mRNA containing pseudouridine prompted nonhuman primates to express two
human proteins.
«Ferritin, a
protein - coated iron storage molecule, is normally found throughout the mouse and
human body, but in our experiments, we
modified it, placing the ferritin particles in different positions to see if we could improve our results,» says co-first author Sarah Stanley, a senior research associate in Friedman's lab.
Whereas in yeast, a histone -
modifying enzyme might have a single regulatory task, the
human version of that same enzyme might have other regulatory tasks that involve additional
proteins.
Your report on detecting longer wavelengths of red light with a
modified human visual
protein (15 December 2012, p 19)...
The team led by Dr Rubén López — of the UAB's Department of Cell Biology, Physiology and Immunology and Institute of Neuroscience, and the Centre for Networked Biomedical Research in Neurodegenerative Diseases (CIBERNED)-- used a genetically
modified mouse that produces the
human form of IL - 37 to study the function of this
protein.
UBC Psychiatry Professor Dr. Weihong Song and Neurology Professor Yan - Jiang Wang at Third Military Medical University in Chongqing attached normal mice, which don't naturally develop Alzheimer's disease, to mice
modified to carry a mutant
human gene that produces high levels of a
protein called amyloid - beta.
«Single enzyme's far - reaching influence in
human biology, disease: Enzyme Fam20C chemically
modifies more than 100 different secreted
proteins, thus directing numerous cellular processes.»
Many of these complexes have proven quite complicated, but scientists have put those involving a
protein called Cas9 to use: deleting,
modifying, and even adding DNA to organisms ranging from yeast to
humans.
But other lipids are known to guide cell migrations in
human brain development, and geneticist Ken Howard of University College London suspects HMG - CoA reductase might help produce a similar lipid molecule or
modify a
protein that attracts the germ cells.
Using studies in both mice and
humans, they found that exposure to farm dust increases expression of a protective
protein that suppresses the inflammatory immune system by
modifying the communication between the lining of the lungs and the immune system.
PROVIDENCE, R.I. [Brown University]-- A new study on the mechanics of aging and longevity finds that fruit flies inhibited from producing the
protein Sirt4 — which is also found in
humans — are short - lived, while flies
modified to make extra Sirt4 are long - lived.
If this technique proves successful, it could lead to better ways on how to
modify the
proteins in cells, or even eliminate cancer cells in
humans.
Our proposal represents the kind of research I am interested in, which seeks to
modify natural
protein variants to be used as therapeutic options for
human brain diseases.
Therefore, Teitell's group opted to further
modify their constructs with a 3 ′ - UTR mitochondrial targeting sequence (MTS) from
human mitochondrial ribosomal
protein S12 — the same essential approach used to optimize the import of allotopically - expressed
proteins by Dr. Marisol Corral - Debrinski, (3,4) and subsequently advanced for multiple additional ETS subunit
proteins by Dr. Matthew O'Connor's group at the SENS Foundation Research Center (RC).
We will be discussing new research published in nature where researchers
modified a
protein associated with Alzheimer's disease into a more harmless form, allowing them to remove the damage caused by Alzheimer's in
human cells.
Genetically
modified goats are an important tool for producing valuable therapeutic
protein [14]--[16] and studying
human diseases as ideal biomedical models [17]--[19].