Our group seeks to investigate the use of chemically -
modified nucleic acid aptamers, single stranded DNA or RNA sequences that specifically bind to a diverse variety of targets, in biosensing and catalysis.
Two projects will be done jointly with the Karolinska Institute in Stockholm: Molecular biologist David Baillie of Simon Fraser University in Burnaby, British Columbia, was awarded $ 6.73 million to study protein function in the soil nematode Caenorhabditis elegans, and microbiologist Sherif Abou Elela of the University of Sherbrooke, Quebec, received $ 3.75 million to test
modified nucleic acid technologies for determining gene function.
Not exact matches
Together with his principal investigator (PI), he had realized the commercial potential of
modifying nanoparticles with
nucleic acids to create targeted, personalized medicines for a myriad of diseases.
The technique introduces
modified segments of
nucleic acid from the gene that produces the nicotine demethylase enzyme.
Our work on PoSTAC (Polycistronic SunTAg
modified CRISPR) has been published in
Nucleic Acids Research.
Nucleic Acid -
Modified Nanostructures as Programmable Atom Equivalents: Forging a New «Table of Elements by Robert J. Macfarlane, Matthew N. O'Brien, Dr. Sarah Hurst Petrosko, and Prof. Chad A. Mirkin.