Not exact matches
Importantly, only approximately one ‐ quarter
of individuals with the
mutations manifest the disease; this incomplete penetrance is also likely a consequence
of the
effects of disease ‐
modifying genes, environmental influences, or both in a given individual.
In addition, a breed can be heterogeneous for other genetic variants that affect hair growth and structure, such as
mutations for hair length and curl, that can
modify effect of the RSPO2
mutation and introduce more variation in coat appearance.