Plakophilin - 3 Catenin Associates with the ETV1 / ER81 Transcription Factor to Positively
Modulate Gene Activity.
Not exact matches
With
gene activity -
modulating parts integrating into the genome with such high efficiency, the researchers were able to randomly generate many different strains of yeast, each with its own unique set of modifications.
The UK patents relate to the CRISPR - Cas9
gene editing systems involving single - guide RNA in both non-cellular and cellular settings (UK Patent No. 2518764) and chimeric CRISPR - Cas9 systems in which the Cas9 protein is modified to provide alternative DNA -
modulating activities (UK Patent No. 2537000).
His lab has extensive experience evaluating and
modulating T cell responses to tumors and viruses, including introducing
genes into T cells to impart specificity and
modulate function, designing strategies to overcome tolerance and enhance in vivo
activity, and developing mouse models that more accurately model human immune responses to candidate vaccines.
If environment affects the regulation of
gene expression and, in turn, the
activity of neurotransmitters that
modulate behavior, this kind of interaction may be a significant factor in the development of criminal and antisocial behavior.