Sentences with phrase «modulating phosphorylation»

Not exact matches

Nucleotides and phosphorylation bi-directionally modulate CaMKII binding to the NMDA - receptor subunit GluN2B.

Nucleotides and phosphorylation bi-directionally modulate Ca2 + / calmodulin - dependent protein kinase II (CaMKII) binding to the N - methyl - D - aspartate (NMDA) receptor subunit GluN2B.

C - Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α - Synuclein in a Yeast Model of Parkinson's Disease.

Espejo AB, Gao G, Black K, Gayatri S, Veland N, Kim J, Chen T, Sudol M, Walker C, Bedford MT. (2017) PRMT5 C - terminal Phosphorylation Modulates a 14 -3-3 / PDZ Interaction Switch.

mTOR - rictor complex (composed of mTOR, rictor, and GβL) is not rapamycin sensitive and modulates cell survival and proliferation by direct phosphorylation of AKT on Ser473 and by facilitating AKT phosphorylation on Thr308 by PDK1 in vitro (13).

J147 also modulates the expression and / or phosphorylation of downstream targets of BDNF [7].

To examine whether lethal toxin modulated JAK2 and / or STAT3 signaling, we next treated MNK - 3 cells with lethal toxin for 2 hr, stimulated with IL - 23 for the indicated time and then examined JAK2 and STAT3 phosphorylation by western blot analyses.

Mutations of Cellulose Synthase (CESA1) Phosphorylation Sites Modulate Anisotropic Cell Expansion and Bidirectional Mobility of Cellulose Synthase, Shaolin Chen, David Eherhardt, Chris Somerville; Proceedings of the National Academy of Sciences, doi / 10.1073 / pnas.1012348107, September 22, 2010.

Roles of «junk phosphorylation» in modulating biomolecular association of phosphorylated proteins?

Having established the importance of the miR - 181a target genes, Smad1 and Smad5, in BMP / GDF ligand - induced neurite growth, we next determined whether miR - 181a - modulated Smad phosphorylation / activation and neurite growth in SH - SY5Y cells, which are a widely used cell line model of human mDA neurons which also express the miR - 181a targets, BMPR2 and Smad1 / 5 [18,38].

Within this broad topic we are particularly interested in characterising (i) the molecular mechanism by which these photoreceptors mediate light - dependent entrainment of the circadian clock, (ii) the components mediating, in a light - quality - dependent fashion, nucleocytoplasmic partitioning of phytochromes and UVR8, (iii) how phosphorylation and sumoylation of these photorecepors and other signalling components modulate red / far - red and UVB - induced signalling, and (iv) to what extent intercellular and cell - autonomous events contribute to phytochrome and UVR8 regulated photomorphogenesis.

During physiological conditions, the functions of tau protein are modulated by the activities of protein kinases and phosphatases that determine the extent of phosphorylation of this protein.